Literature DB >> 21728973

Nitric oxide and cyclic GMP signaling pathway as a focus for drug development.

A Y Kots1, K Bian, F Murad.   

Abstract

Recent progress in understanding of the nitric oxide and cGMP signaling pathway provided evidence for mechanism of action of known drugs and identified novel targets for drug development. These discoveries resulted in numerous efforts in drug and formulation discovery. Some of the most promising approaches were applied for efficient therapies of various diseases.

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Year:  2011        PMID: 21728973     DOI: 10.2174/092986711796504646

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  11 in total

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2.  Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα.

Authors:  Thomas M Moon; Nathan R Tykocki; Jessica L Sheehe; Brent W Osborne; Werner Tegge; Joseph E Brayden; Wolfgang R Dostmann
Journal:  Chem Biol       Date:  2015-12-17

3.  Nitric oxide-eluting nanocomposite for cardiovascular implants.

Authors:  Achala de Mel; Noora Naghavi; Brian G Cousins; Innes Clatworthy; George Hamilton; Arnold Darbyshire; Alexander M Seifalian
Journal:  J Mater Sci Mater Med       Date:  2013-11-30       Impact factor: 3.896

Review 4.  Stimulators and activators of soluble guanylate cyclase for urogenital disorders.

Authors:  Fabiola Z Mónica; Edson Antunes
Journal:  Nat Rev Urol       Date:  2017-11-14       Impact factor: 14.432

5.  Regulation of sGC via hsp90, Cellular Heme, sGC Agonists, and NO: New Pathways and Clinical Perspectives.

Authors:  Arnab Ghosh; Dennis J Stuehr
Journal:  Antioxid Redox Signal       Date:  2016-05-02       Impact factor: 8.401

Review 6.  Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells.

Authors:  Amparo Beltran-Povea; Estefania Caballano-Infantes; Carmen Salguero-Aranda; Franz Martín; Bernat Soria; Francisco J Bedoya; Juan R Tejedo; Gladys M Cahuana
Journal:  World J Stem Cells       Date:  2015-04-26       Impact factor: 5.326

7.  Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.

Authors:  Arnab Ghosh; Johannes-Peter Stasch; Andreas Papapetropoulos; Dennis J Stuehr
Journal:  J Biol Chem       Date:  2014-04-14       Impact factor: 5.157

8.  PDE5 inhibitors enhance celecoxib killing in multiple tumor types.

Authors:  Laurence Booth; Jane L Roberts; Nichola Cruickshanks; Seyedmehrad Tavallai; Timothy Webb; Peter Samuel; Adam Conley; Brittany Binion; Harold F Young; Andrew Poklepovic; Sarah Spiegel; Paul Dent
Journal:  J Cell Physiol       Date:  2015-05       Impact factor: 6.384

9.  Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

Authors:  Cinzia Fionda; Maria Pia Abruzzese; Alessandra Zingoni; Alessandra Soriani; Biancamaria Ricci; Rosa Molfetta; Rossella Paolini; Angela Santoni; Marco Cippitelli
Journal:  BMC Cancer       Date:  2015-01-22       Impact factor: 4.430

10.  Nexavar/Stivarga and viagra interact to kill tumor cells.

Authors:  Mehrad Tavallai; Hossein A Hamed; Jane L Roberts; Nichola Cruickshanks; John Chuckalovcak; Andrew Poklepovic; Laurence Booth; Paul Dent
Journal:  J Cell Physiol       Date:  2015-09       Impact factor: 6.384

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