OBJECTIVE: To assess whether the Pfirrmann system for grading lumbar intervertebral disk (IVD) degeneration in humans can also be used in dogs. ANIMALS: 202 dogs. PROCEDURES: Magnetic resonance imaging was used to obtain images of vertebral segments from dogs, which were reviewed separately by 3 observers who graded the extent of degeneration in each visible IVD by use of the Pfirrmann classification system used for grading lumbar IVD degeneration in humans. Grading was validated against 2 factors associated with the extent of disk degeneration: type of dog (chondrodystrophic or nonchondrodystrophic breeds) and age. RESULTS: Interobserver and intraobserver agreement for Pfirrmann grading of IVD degeneration were good (κ scores, 0.81 to 0.93). An increase in the extent of disk degeneration was positively correlated with increases in age and with chondrodystrophic breed. CONCLUSIONS AND CLINICAL RELEVANCE: The Pfirrmann system was reliably used to grade IVD degeneration in dogs of various breeds and ages. An increase in the extent of IVD degeneration was positively correlated with increases in age and with chondrodystrophic-type dogs.
OBJECTIVE: To assess whether the Pfirrmann system for grading lumbar intervertebral disk (IVD) degeneration in humans can also be used in dogs. ANIMALS: 202 dogs. PROCEDURES: Magnetic resonance imaging was used to obtain images of vertebral segments from dogs, which were reviewed separately by 3 observers who graded the extent of degeneration in each visible IVD by use of the Pfirrmann classification system used for grading lumbar IVD degeneration in humans. Grading was validated against 2 factors associated with the extent of disk degeneration: type of dog (chondrodystrophic or nonchondrodystrophic breeds) and age. RESULTS: Interobserver and intraobserver agreement for Pfirrmann grading of IVD degeneration were good (κ scores, 0.81 to 0.93). An increase in the extent of disk degeneration was positively correlated with increases in age and with chondrodystrophic breed. CONCLUSIONS AND CLINICAL RELEVANCE: The Pfirrmann system was reliably used to grade IVD degeneration in dogs of various breeds and ages. An increase in the extent of IVD degeneration was positively correlated with increases in age and with chondrodystrophic-typedogs.
Authors: Nicole Willems; Frances C Bach; Saskia G M Plomp; Mattie H P van Rijen; Jeannette Wolfswinkel; Guy C M Grinwis; Clemens Bos; Gustav J Strijkers; Wouter J A Dhert; Björn P Meij; Laura B Creemers; Marianna A Tryfonidou Journal: Arthritis Res Ther Date: 2015-05-27 Impact factor: 5.156
Authors: Nicole Willems; Hsiao-Yin Yang; Marloes L P Langelaan; Anna R Tellegen; Guy C M Grinwis; Hendrik-Jan C Kranenburg; Frank M Riemers; Saskia G M Plomp; Eric G M Craenmehr; Wouter J A Dhert; Nicole E Papen-Botterhuis; Björn P Meij; Laura B Creemers; Marianna A Tryfonidou Journal: Arthritis Res Ther Date: 2015-08-20 Impact factor: 5.156
Authors: Lisa K Harder; Davina C Ludwig; Vladimir Galindo-Zamora; Ingo Nolte; Patrick Wefstaedt Journal: BMC Vet Res Date: 2015-05-14 Impact factor: 2.741