Literature DB >> 21727970

A synergistic approach to polycyclics via a strategic utilization of Claisen rearrangement and olefin metathesis.

Sambasivarao Kotha1, Nimita G Krishna, Somnath Halder, Shilpi Misra.   

Abstract

Olefin metathesis promoted by a well-defined metal carbene complex has evolved into an efficient method for the construction of a broad range of carbocyclic and heterocyclic rings of varying size. The synthetic potential of the olefin metathesis has been further increased by combining various other C-C bond forming processes either in tandem or in sequence. Herein, application of Claisen rearrangement and olefin metathesis to prepare various intricate and/or biologically important targets has been described.

Entities:  

Year:  2011        PMID： 21727970     DOI： 10.1039/c1ob05413a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  8 in total

1.  Design and synthesis of polycyclic sulfones via Diels-Alder reaction and ring-rearrangement metathesis as key steps.

Authors:  Sambasivarao Kotha; Rama Gunta
Journal:  Beilstein J Org Chem       Date:  2015-08-06       Impact factor: 2.883

2.  Synthesis of Dihydrooxepino[3,2-c]Pyrazoles via Claisen Rearrangement and Ring-Closing Metathesis from 4-Allyloxy-1H-pyrazoles.

Authors:  Yoshihide Usami; Aoi Kohno; Hiroki Yoneyama; Shinya Harusawa
Journal:  Molecules       Date:  2018-03-06       Impact factor: 4.411

3.  One-pot thiol-free synthetic approach to sulfides, and sulfoxides selectively.

Authors:  Sambasivarao Kotha; Naveen Kumar Gupta; Saima Ansari
Journal:  RSC Adv       Date:  2022-09-05       Impact factor: 4.036

4.  Bridgehead vicinal diallylation of norbornene derivatives and extension to propellane derivatives via ring-closing metathesis.

Authors:  Sambasivarao Kotha; Rama Gunta
Journal:  Beilstein J Org Chem       Date:  2016-08-22       Impact factor: 2.883

5.  Design and synthesis of propellane derivatives and oxa-bowls via ring-rearrangement metathesis as a key step.

Authors:  Sambasivarao Kotha; Rama Gunta
Journal:  Beilstein J Org Chem       Date:  2015-09-24       Impact factor: 2.883

6.  Recent developments in the Reformatsky-Claisen rearrangement.

Authors:  Jun Ishihara; Susumi Hatakeyama
Journal:  Molecules       Date:  2012-11-30       Impact factor: 4.411

7.  Tandem RCM-Claisen rearrangement-[2+2] cycloaddition of O,O'-(but-2-en-1,4-diyl)-bridged binaphthols.

Authors:  Michael Abraham; Wolfgang Reischl; Karl A Kirchner; Alexander Roller; Luis F Veiros; Michael Widhalm
Journal:  Molecules       Date:  2012-12-07       Impact factor: 4.411

8.  Synthetic Approach to the ABCD Ring System of Anticancer Agent Fredericamycin A via Claisen Rearrangement and Ring-Closing Metathesis as Key Steps.

Authors:  Sambasivarao Kotha; Subba Rao Cheekatla; Ambareen Fatma
Journal:  ACS Omega       Date:  2019-10-14
  8 in total

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