Literature DB >> 2172544

Effect of virus dose and nonoxynol-9 on the genital transmission of SIV in rhesus macaques.

C J Miller1, N J Alexander, S Sutjipto, S M Joye, A G Hendrickx, M Jennings, P A Marx.   

Abstract

One inoculation of cell-free SIVmac (50 TCID50) caused persistent viremia in nine of 13 female rhesus macaques inoculated intravaginally. Persistent viremia was produced in two of four male rhesus macaques by twice placing cell-free SIVMAC (50 TCID50) onto the skin and urethral os of the penis. Placing a spermicide containing nonoxynol-9 into the vaginal canal prior to repeated intravaginal inoculations of SIV prevented transmission of the virus in three of six female rhesus macaques.

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Year:  1990        PMID： 2172544

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  26 in total

1.  The Development of Microbicides for Clinical Use to Prevent Sexually Transmitted Diseases.

Authors:  David M. Phillips; Robin A. Maguire
Journal:  Curr Infect Dis Rep       Date:  2002-04       Impact factor: 3.725

2.  Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus.

Authors:  Christopher J Miller; Qingsheng Li; Kristina Abel; Eun-Young Kim; Zhong-Min Ma; Stephen Wietgrefe; Lisa La Franco-Scheuch; Lara Compton; Lijie Duan; Marta Dykhuizen Shore; Mary Zupancic; Marc Busch; John Carlis; Steven Wolinsky; Steven Wolinksy; Ashley T Haase
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

3.  Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239.

Authors:  C J Miller; M B McChesney; X Lü; P J Dailey; C Chutkowski; D Lu; P Brosio; B Roberts; Y Lu
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

4.  Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques.

Authors:  Y Lu; P Brosio; M Lafaile; J Li; R G Collman; J Sodroski; C J Miller
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

5.  Pathogenic consequences of vaginal infection with CCR5-tropic simian-human immunodeficiency virus SHIVSF162P3N.

Authors:  Madina Shakirzyanova; Lily Tsai; Wuze Ren; Agegneu Gettie; James Blanchard; Cecilia Cheng-Mayer
Journal:  J Virol       Date:  2012-06-27       Impact factor: 5.103

6.  Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells.

Authors:  Michael D Bobardt; Udayan Chatterji; Suganya Selvarajah; Bernadette Van der Schueren; Guido David; Bruce Kahn; Philippe A Gallay
Journal:  J Virol       Date:  2006-10-18       Impact factor: 5.103

7.  Comparative investigation of Langerhans' cells and potential receptors for HIV in oral, genitourinary and rectal epithelia.

Authors:  L A Hussain; T Lehner
Journal:  Immunology       Date:  1995-07       Impact factor: 7.397

8.  Development of simian immunodeficiency virus isolation, titration, and neutralization assays which use whole blood from rhesus monkeys and an antigen capture enzyme-linked immunosorbent assay.

Authors:  B L Lohman; J Higgins; M L Marthas; P A Marx; N C Pedersen
Journal:  J Clin Microbiol       Date:  1991-10       Impact factor: 5.948

9.  Intravaginal inoculation of rhesus macaques with cell-free simian immunodeficiency virus results in persistent or transient viremia.

Authors:  C J Miller; M Marthas; J Torten; N J Alexander; J P Moore; G F Doncel; A G Hendrickx
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

10.  The relationship between simian immunodeficiency virus RNA levels and the mRNA levels of alpha/beta interferons (IFN-alpha/beta) and IFN-alpha/beta-inducible Mx in lymphoid tissues of rhesus macaques during acute and chronic infection.

Authors:  Kristina Abel; Michelle J Alegria-Hartman; Kristina Rothaeusler; Marta Marthas; Christopher J Miller
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103
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