Literature DB >> 2172539

Mesenchymoproliferative disorders (MPD) in simian AIDS associated with SRV-2 infection.

C C Tsai1, C C Tsai1, S T Roodman, M D Woon.   

Abstract

We have observed several mesenchymal proliferative disorders (MPD) in macaques with SAIDS associated with SRV-2 infection. Retroperitoneal and subcutaneous fibromatosis, progressive fibrovascular proliferation, mimicking Kaposi's sarcoma, were seen in 165 macaques. Three obliterative fibrointimal proliferative arteriopathies and one congenital pulmonary sequestration with extensive MPD were observed in SRV-2 positive monkeys. Continuous cell lines were established and SRV-2 was identified in all tissues and cell lines. Immunophenotyping of the cultured cells showed heterogeneous mesenchymal cells. Xenograft and allograft transplantation of cultured cells produced MPD lesions in the recipients. The data suggest that SRV-2 plays an important role in the etiopathogenesis of MPD in macaques.

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Year:  1990        PMID： 2172539

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  7 in total

1.  Simian retrovirus serogroup 5: partial gag-prt sequence and viral RNA distribution in an infected rhesus macaque.

Authors:  B Li; M K Axthelm; C A Machida
Journal:  Virus Genes       Date:  2000-10       Impact factor: 2.332

2.  Two distinct gamma-2 herpesviruses in African green monkeys: a second gamma-2 herpesvirus lineage among old world primates?

Authors:  J Greensill; J A Sheldon; N M Renwick; B E Beer; S Norley; J Goudsmit; T F Schulz
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

3.  Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species.

Authors:  T M Rose; K B Strand; E R Schultz; G Schaefer; G W Rankin; M E Thouless; C C Tsai; M L Bosch
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

4.  Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.

Authors:  R P Searles; E P Bergquam; M K Axthelm; S W Wong
Journal:  J Virol       Date:  1999-04       Impact factor: 5.103

5.  Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD).

Authors:  B U Orzechowska; M Manoharan; J Sprague; R D Estep; M K Axthelm; S W Wong
Journal:  J Med Primatol       Date:  2009-10       Impact factor: 0.667

6.  Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.

Authors:  G H Marracci; R D Kelley; K Y Pilcher; L Crabtree; S M Shiigi; N Avery; G Leo; M C Webb; L M Hallick; M K Axthelm
Journal:  J Virol       Date:  1995-04       Impact factor: 5.103

7.  Induction of B cell hyperplasia in simian immunodeficiency virus-infected rhesus macaques with the simian homologue of Kaposi's sarcoma-associated herpesvirus.

Authors:  S W Wong; E P Bergquam; R M Swanson; F W Lee; S M Shiigi; N A Avery; J W Fanton; M K Axthelm
Journal:  J Exp Med       Date:  1999-09-20       Impact factor: 14.307
  7 in total

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