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Literature DB >> 21725286

Multi-talented MCAK: Microtubule depolymerizer with a strong grip.

Abstract

Microtubule-depolymerizing motor proteins regulate microtubule dynamics during chromosome segregation, but whether they can independently grip the ends of shrinking kinetochore microtubules has remained unresolved. MCAK, a member of the kinesin-13 motor protein family, is now shown to grip microtubules on its own and harness the forces of microtubule disassembly.

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Year: 2011 PMID： 21725286 DOI： 10.1038/ncb0711-738

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

15 in total

1. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.

Authors: Gregory C Rogers; Stephen L Rogers; Tamara A Schwimmer; Stephanie C Ems-McClung; Claire E Walczak; Ronald D Vale; Jonathan M Scholey; David J Sharp
Journal: Nature Date: 2003-12-14 Impact factor: 49.962

Review 2. Tubulin depolymerization may be an ancient biological motor.

Authors: J Richard McIntosh; Vladimir Volkov; Fazly I Ataullakhanov; Ekaterina L Grishchuk
Journal: J Cell Sci Date: 2010-10-15 Impact factor: 5.285

3. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends.

Authors: Jonne Helenius; Gary Brouhard; Yannis Kalaidzidis; Stefan Diez; Jonathon Howard
Journal: Nature Date: 2006-05-04 Impact factor: 49.962

4. XMAP215 is a processive microtubule polymerase.

Authors: Gary J Brouhard; Jeffrey H Stear; Tim L Noetzel; Jawdat Al-Bassam; Kazuhisa Kinoshita; Stephen C Harrison; Jonathon Howard; Anthony A Hyman
Journal: Cell Date: 2008-01-11 Impact factor: 41.582

5. Kin I kinesins are microtubule-destabilizing enzymes.

Authors: A Desai; S Verma; T J Mitchison; C E Walczak
Journal: Cell Date: 1999-01-08 Impact factor: 41.582

6. The bidirectional depolymerizer MCAK generates force by disassembling both microtubule ends.

Authors: Yusuke Oguchi; Seiichi Uchimura; Takashi Ohki; Sergey V Mikhailenko; Shin'ichi Ishiwata
Journal: Nat Cell Biol Date: 2011-05-22 Impact factor: 28.824

7. Direct observation of the binding state of the kinesin head to the microtubule.

Authors: Nicholas R Guydosh; Steven M Block
Journal: Nature Date: 2009-08-19 Impact factor: 49.962

8. The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.

Authors: Andrew F Powers; Andrew D Franck; Daniel R Gestaut; Jeremy Cooper; Beth Gracyzk; Ronnie R Wei; Linda Wordeman; Trisha N Davis; Charles L Asbury
Journal: Cell Date: 2009-03-06 Impact factor: 41.582

9. Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movement.

Authors: Paula M Grissom; Thomas Fiedler; Ekaterina L Grishchuk; Daniela Nicastro; Robert R West; J Richard McIntosh
Journal: Mol Biol Cell Date: 2008-11-26 Impact factor: 4.138

10. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis.

Authors: L Wordeman; T J Mitchison
Journal: J Cell Biol Date: 1995-01 Impact factor: 10.539

2 in total

Review 1. Prime movers: the mechanochemistry of mitotic kinesins.

Authors: Robert A Cross; Andrew McAinsh
Journal: Nat Rev Mol Cell Biol Date: 2014-04 Impact factor: 94.444

2. Identification of genes associated with clinicopathological features of colorectal cancer.

Authors: Xiaoting Wang; Shouzi Hu; Wenbin Ji; Yan Tang; Shulong Zhang
Journal: J Int Med Res Date: 2020-04 Impact factor: 1.671

2 in total