| Literature DB >> 21722881 |
Sanjoy Kumar Bhunia1, Biswajit Dey, Kankan K Maity, Sukesh Patra, Soumitra Mandal, Swatilekha Maiti, Tapas K Maiti, Samir R Sikdar, Syed S Islam.
Abstract
A water-soluble glucan, isolated from the alkaline extract of the fruit bodies of an edible mushroom, Lentinus squarrosulus (Mont.) Singer was found to consist of (1→3,6)-linked, (1→3)-linked, (1→6)-linked, and terminal β-d-glucopyranosyl moieties in a relative proportion of approximately 1:2:1:1. This polysaccharide showed optimum activation of macrophages as well as splenocytes and thymocytes at 10μg/mL. Structural investigation was carried out using sugar analysis, methylation analysis, periodate oxidation study, and NMR experiments ((1)H, (13)C, DEPT-135, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC). On the basis of above-mentioned experiments, the structure of the repeating unit of the polysaccharide was established as:Entities:
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Year: 2011 PMID： 21722881 DOI： 10.1016/j.carres.2011.05.029
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104