| Literature DB >> 21722688 |
E S Pronker1, T C Weenen, H R Commandeur, A D M E Osterhaus, H J H M Claassen.
Abstract
Gold dimensions of pharmaceutical drug development indicate that it takes on average 11.9 years, with an investment around US$ 0.8 Billion, to launch one product on the market. Furthermore, approximately 22% of the drug candidates successfully complete clinical testing. These universally acknowledged proportions largely originate from one single, much cited publication; Dimasi et al. [5]. However an additional six articles describing new chemical entities (NCE) development were identified, which contain little, if any, information on vaccines. Published cumulative success rates range from 7% to 78% and investments calculations span US$ 0.8 to 1.7 Billion. Obviously this disserves further clarification?Mesh：
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Year: 2011 PMID： 21722688 DOI： 10.1016/j.vaccine.2011.06.051
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641