CLINICAL QUESTION: What is the role of steroids in septic shock in the emergency department? ARTICLE CHOSEN: Sprung CL, Annane D, Keh D, et al; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008;358:111-24. STUDY OBJECTIVE: To assess the safety and efficacy of low-dose hydrocortisone therapy for patients with septic shock and to compare outcomes based on response to corticotropin testing.
CLINICAL QUESTION: What is the role of steroids in septic shock in the emergency department? ARTICLE CHOSEN: Sprung CL, Annane D, Keh D, et al; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008;358:111-24. STUDY OBJECTIVE: To assess the safety and efficacy of low-dose hydrocortisone therapy for patients with septic shock and to compare outcomes based on response to corticotropin testing.
Authors: Pedro Póvoa; Jorge I F Salluh; Maria L Martinez; Raquel Guillamat-Prats; Dianne Gallup; Hussein R Al-Khalidi; B Taylor Thompson; V Marco Ranieri; Antonio Artigas Journal: Crit Care Date: 2015-04-28 Impact factor: 9.097