BACKGROUND AND AIMS: Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx), as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the changes of HVPG and liver function. PATIENTS AND METHODS: B-RTO was performed in 30 patients with GVx and hepatic encephalopathy. HVPG was measured in 19 of 30 patients both before and after B-RTO. RESULTS: The B-RTO was successful in all patients. The GVx and hepatic encephalopathy were improved, and no recurrence or bleeding was observed within the follow- up period. The serum albumin and prothrombin activity were significantly improved 6 months after B-RTO in all patients. HVPG was elevated 44% above the baseline after B-RTO. Liver function significantly improved 6 months after B-RTO in patients whose HVPG increased ≥ 20% from baseline. CONCLUSION: An elevated HVPG after B-RTO is one aspect of the effect of liver function, and an HVPG increase of ≥ 20% from baseline is a predictive factor for obtaining an improvement of liver function.
BACKGROUND AND AIMS: Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx), as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the changes of HVPG and liver function. PATIENTS AND METHODS: B-RTO was performed in 30 patients with GVx and hepatic encephalopathy. HVPG was measured in 19 of 30 patients both before and after B-RTO. RESULTS: The B-RTO was successful in all patients. The GVx and hepatic encephalopathy were improved, and no recurrence or bleeding was observed within the follow- up period. The serum albumin and prothrombin activity were significantly improved 6 months after B-RTO in all patients. HVPG was elevated 44% above the baseline after B-RTO. Liver function significantly improved 6 months after B-RTO in patients whose HVPG increased ≥ 20% from baseline. CONCLUSION: An elevated HVPG after B-RTO is one aspect of the effect of liver function, and an HVPG increase of ≥ 20% from baseline is a predictive factor for obtaining an improvement of liver function.
Authors: Jonathan K Park; Sammy Saab; Stephen T Kee; Ronald W Busuttil; Hyun J Kim; Francsico Durazo; Sung-Ki Cho; Edward Wolfgang Lee Journal: Dig Dis Sci Date: 2014-12-18 Impact factor: 3.199
Authors: Se Young Jang; Go Heun Kim; Soo Young Park; Chang Min Cho; Won Young Tak; Jeong Han Kim; Won Hyeok Choe; So Young Kwon; Jae Myeong Lee; Sang Gyune Kim; Dae Yong Kim; Young Seok Kim; Se-Ok Lee; Yang Won Min; Joon Hyeok Lee; Seung Woon Paik; Byung Chul Yoo; Jae Wan Lim; Hong Joo Kim; Yong Kyun Cho; Joo Hyun Sohn; Jae Yoon Jeong; Yu Hwa Lee; Tae Yeob Kim; Young Oh Kweon Journal: Clin Mol Hepatol Date: 2012-12-21