Literature DB >> 2172157

Superoxide generation by EBV-transformed B lymphocytes. Activation by IL-1 beta, TNF-alpha and receptor independent stimuli.

J T Hancock1, L M Henderson, O T Jones.   

Abstract

The generation of superoxide by Epstein-Barr virus (EBV)-transformed human B lymphocytes can be stimulated by a range of compounds; receptor-dependent stimuli include tumour necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta) and lipopolysaccharides (LPS), and independent stimuli include AlF3, A21387 and ionomycin. The stimuli suggest that the activation pathway for the lymphocyte oxidase is similar to that proposed for the neutrophil oxidase. Although the rate of superoxide production was lower than that by neutrophils, the respiratory burst was much prolonged. It is possible that this superoxide generation by lymphocytes may have a biological function.

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Year:  1990        PMID： 2172157      PMCID： PMC1384306     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  39 in total

1.  The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes.

Authors:  A J SBARRA; M L KARNOVSKY
Journal:  J Biol Chem       Date:  1959-06       Impact factor: 5.157

Review 2.  Pathways of oxygen utilization by stimulated platelets and leukocytes.

Authors:  A J Marcus
Journal:  Semin Hematol       Date:  1979-07       Impact factor: 3.851

3.  Long-term T-cell-mediated immunity to Epstein-Barr virus in man. I. Complete regression of virus-induced transformation in cultures of seropositive donor leukocytes.

Authors:  D J Moss; A B Rickinson; J H Pope
Journal:  Int J Cancer       Date:  1978-12       Impact factor: 7.396

Review 4.  Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase.

Authors:  A G Gilman
Journal:  J Clin Invest       Date:  1984-01       Impact factor: 14.808

Review 5.  The role of protein kinase C in cell surface signal transduction and tumour promotion.

Authors:  Y Nishizuka
Journal:  Nature       Date:  1984 Apr 19-25       Impact factor: 49.962

Review 6.  Active oxygen species and the functions of phagocytic leukocytes.

Authors:  J A Badwey; M L Karnovsky
Journal:  Annu Rev Biochem       Date:  1980       Impact factor: 23.643

7.  The enzymic reduction and kinetics of oxidation of cytochrome b-245 of neutrophils.

Authors:  A R Cross; F K Higson; O T Jones; A M Harper; A W Segal
Journal:  Biochem J       Date:  1982-05-15       Impact factor: 3.857

8.  B cell lines as models for inherited phagocytic diseases: abnormal superoxide generation in chronic granulomatous disease and giant granules in Chediak-Higashi syndrome.

Authors:  D J Volkman; E S Buescher; J I Gallin; A S Fauci
Journal:  J Immunol       Date:  1984-12       Impact factor: 5.422

9.  Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes.

Authors:  J T Curnutte; B M Babior
Journal:  J Clin Invest       Date:  1974-06       Impact factor: 14.808

10.  Exposure of human neutrophils to chemotactic factors potentiates activation of the respiratory burst enzyme.

Authors:  J G Bender; L C McPhail; D E Van Epps
Journal:  J Immunol       Date:  1983-05       Impact factor: 5.422
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  6 in total

1.  Voltage-activated proton currents in human lymphocytes.

Authors:  Tom Schilling; Alexander Gratopp; Thomas E DeCoursey; Claudia Eder
Journal:  J Physiol       Date:  2002-11-15       Impact factor: 5.182

2.  Production of extracellular superoxide by human lymphoblast cell lines: comparison of electron spin resonance techniques and cytochrome C reduction assay.

Authors:  Sergey I Dikalov; Wei Li; Payam Mehranpour; Shaoshan S Wang; A Maziar Zafari
Journal:  Biochem Pharmacol       Date:  2006-12-15       Impact factor: 5.858

3.  O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA.

Authors:  S J Chanock; L R Faust; D Barrett; C Bizal; F E Maly; P E Newburger; J M Ruedi; R M Smith; B M Babior
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

4.  Phosphorylation of p47phox is required for receptor-mediated NADPH oxidase/NOX2 activation in Epstein-Barr virus-transformed human B lymphocytes.

Authors:  Sahra Amel Belambri; Margarita Hurtado-Nedelec; Abderrahmane Senator; Karama Makni-Maalej; Michèle Fay; Marie-Anne Gougerot-Pocidalo; Jean-Claude Marie; Pham My-Chan Dang; Jamel El-Benna
Journal:  Am J Blood Res       Date:  2012-10-20

5.  In vitro molecular reconstitution of the respiratory burst in B lymphoblasts from p47-phox-deficient chronic granulomatous disease.

Authors:  B D Volpp; Y Lin
Journal:  J Clin Invest       Date:  1993-01       Impact factor: 14.808

6.  The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.

Authors:  Samantha D Pauls; Sandrine T Lafarge; Ivan Landego; Tingting Zhang; Aaron J Marshall
Journal:  Front Immunol       Date:  2012-08-09       Impact factor: 7.561
  6 in total

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