| Literature DB >> 2172009 |
Abstract
A hypothesis for the pathobiochemical mechanism of CO poisoning, amenable to in vivo testing with optical reflectance spectrophotometry, is presented. It differs from the classical formulation in which loss of cytochrome c oxidase function is attributed entirely to O2 depletion, by including ligation and oxygenation of CO as essential components of the inhibitory process.Entities:
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Year: 1990 PMID： 2172009 DOI： 10.1016/0014-5793(90)80436-m
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124