| Literature DB >> 21720044 |
Hairin Taha1, A Hamid A Hadi, Noraziah Nordin, Ibrahim A Najmuldeen, Khalit Mohamad, Osamu Shirota, Alfarius E Nugroho, Wong Chin Piow, Toshio Kaneda, Hiroshi Morita.
Abstract
Pseuduvarines A (1) and B (2), two new dioxoaporphine alkaloids with an amino moiety, were isolated from the stem bark of Pseuduvaria rugosa and their structures were elucidated by combination of 2D-NMR spectroscopic analysis. Pseuduvarines A (1) and B (2) showed cytotoxicity against MCF7, HepG2, and HL-60 (1: IC₅₀, 0.9, 21.7, and >50.0 µM, respectively, 2: IC₅₀ >50.0, 15.7, and 12.4 µM, respectively).Entities:
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Year: 2011 PMID： 21720044 DOI： 10.1248/cpb.59.896
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645