Literature DB >> 21719305

MafA and MafB activity in pancreatic β cells.

Yan Hang1, Roland Stein.   

Abstract

Analyses in mouse models have revealed crucial roles for MafA (musculoaponeurotic fibrosarcoma oncogene family A) and MafB in islet β cells, with MafB being required during development and MafA in adults. These two closely related transcription factors regulate many genes essential for glucose sensing and insulin secretion in a cooperative and sequential manner. Significantly, the switch from MafB to MafA expression also appears to be vital for functional maturation of β cells produced by human embryonic stem (hES) cell differentiation. This review summarizes the discovery, distribution, and function of MafA and MafB in rodent pancreatic β cells, and describes some key questions regarding their importance to β cells.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21719305      PMCID： PMC3189696          DOI： 10.1016/j.tem.2011.05.003

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  120 in total

1.  Development of the endocrine pancreas.

Authors:  G Gradwohl
Journal:  Diabetes Metab       Date:  2006-12       Impact factor: 6.041

2.  Islet cell differentiation in liver by combinatorial expression of transcription factors neurogenin-3, BETA2, and RIPE3b1.

Authors:  Young-Duk Song; Eun-Jig Lee; Parham Yashar; Liza E Pfaff; So-Youn Kim; J Larry Jameson
Journal:  Biochem Biophys Res Commun       Date:  2007-01-10       Impact factor: 3.575

3.  Development of macrophages with altered actin organization in the absence of MafB.

Authors:  Athar Aziz; Laurent Vanhille; Peer Mohideen; Louise M Kelly; Claas Otto; Youssef Bakri; Noushine Mossadegh; Sandrine Sarrazin; Michael H Sieweke
Journal:  Mol Cell Biol       Date:  2006-09       Impact factor: 4.272

4.  MafA differentiates rat intestinal cells into insulin-producing cells.

Authors:  Satoshi Nomura; Takaaki Nakamura; Tetsuya Hashimoto; Yoshihiko Nishio; Hiroshi Maegawa; Motoi Kudo; Atsunori Kashiwagi
Journal:  Biochem Biophys Res Commun       Date:  2006-08-14       Impact factor: 3.575

5.  MAFA controls genes implicated in insulin biosynthesis and secretion.

Authors:  H Wang; T Brun; K Kataoka; A J Sharma; C B Wollheim
Journal:  Diabetologia       Date:  2006-12-06       Impact factor: 10.122

6.  Glucose induces MafA expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway.

Authors:  Nathan L Vanderford; Sreenath S Andrali; Sabire Ozcan
Journal:  J Biol Chem       Date:  2006-12-01       Impact factor: 5.157

7.  Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.

Authors:  Kevin A D'Amour; Anne G Bang; Susan Eliazer; Olivia G Kelly; Alan D Agulnick; Nora G Smart; Mark A Moorman; Evert Kroon; Melissa K Carpenter; Emmanuel E Baetge
Journal:  Nat Biotechnol       Date:  2006-10-19       Impact factor: 54.908

8.  Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

Authors:  Päivi J Miettinen; Jarkko Ustinov; Päivi Ormio; Ru Gao; Jaan Palgi; Elina Hakonen; Lisa Juntti-Berggren; Per-Olof Berggren; Timo Otonkoski
Journal:  Diabetes       Date:  2006-12       Impact factor: 9.461

9.  FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

Authors:  Jeffrey C Raum; Kevin Gerrish; Isabella Artner; Eva Henderson; Min Guo; Lori Sussel; Jonathan C Schisler; Christopher B Newgard; Roland Stein
Journal:  Mol Cell Biol       Date:  2006-08       Impact factor: 4.272

10.  A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.

Authors:  Wataru Nishimura; Takuma Kondo; Therese Salameh; Ilham El Khattabi; Rikke Dodge; Susan Bonner-Weir; Arun Sharma
Journal:  Dev Biol       Date:  2006-04-03       Impact factor: 3.582
View more
  99 in total

Review 1.  Lineage determinants in early endocrine development.

Authors:  Sebastian Rieck; Eric D Bankaitis; Christopher V E Wright
Journal:  Semin Cell Dev Biol       Date:  2012-06-21       Impact factor: 7.727

2.  The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis.

Authors:  Maigen Bethea; Yanping Liu; Alexa K Wade; Rachel Mullen; Rajesh Gupta; Vasily Gelfanov; Richard DiMarchi; Sushant Bhatnagar; Richard Behringer; Kirk M Habegger; Chad S Hunter
Journal:  Am J Physiol Endocrinol Metab       Date:  2019-01-08       Impact factor: 4.310

Review 3.  Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells.

Authors:  Gopika Nair; Matthias Hebrok
Journal:  Curr Opin Genet Dev       Date:  2015-04-21       Impact factor: 5.578

4.  Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.

Authors:  Chen Huang; Emily M Walker; Prasanna K Dadi; Ruiying Hu; Yanwen Xu; Wenjian Zhang; Tiziana Sanavia; Jisoo Mun; Jennifer Liu; Gopika G Nair; Hwee Yim Angeline Tan; Sui Wang; Mark A Magnuson; Christian J Stoeckert; Matthias Hebrok; Maureen Gannon; Weiping Han; Roland Stein; David A Jacobson; Guoqiang Gu
Journal:  Dev Cell       Date:  2018-04-12       Impact factor: 12.270

5.  Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.

Authors:  Xiangwei Xiao; Ping Guo; Chiyo Shiota; Ting Zhang; Gina M Coudriet; Shane Fischbach; Krishna Prasadan; Joseph Fusco; Sabarinathan Ramachandran; Piotr Witkowski; Jon D Piganelli; George K Gittes
Journal:  Cell Stem Cell       Date:  2018-01-04       Impact factor: 24.633

6.  MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells.

Authors:  Xiaomin Zhao; Ramkumar Mohan; Sabire Özcan; Xiaoqing Tang
Journal:  J Biol Chem       Date:  2012-06-25       Impact factor: 5.157

7.  Epidermal differentiation gene regulatory networks controlled by MAF and MAFB.

Authors:  Andrew T Labott; Vanessa Lopez-Pajares
Journal:  Cell Cycle       Date:  2016-04-20       Impact factor: 4.534

8.  Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response.

Authors:  Xiaodun Yang; Sarah M Graff; Cody N Heiser; Kung-Hsien Ho; Bob Chen; Alan J Simmons; Austin N Southard-Smith; Gregory David; David A Jacobson; Irina Kaverina; Christopher V E Wright; Ken S Lau; Guoqiang Gu
Journal:  Diabetes       Date:  2020-04-03       Impact factor: 9.461

9.  Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.

Authors:  Taku Kaitsuka; Hirofumi Noguchi; Nobuaki Shiraki; Takuya Kubo; Fan-Yan Wei; Farzana Hakim; Shoen Kume; Kazuhito Tomizawa
Journal:  Stem Cells Transl Med       Date:  2013-11-29       Impact factor: 6.940

10.  The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice.

Authors:  Jaroslawna Meister; Diana Le Duc; Albert Ricken; Ralph Burkhardt; Joachim Thiery; Helga Pfannkuche; Tobias Polte; Johannes Grosse; Torsten Schöneberg; Angela Schulz
Journal:  J Biol Chem       Date:  2014-07-03       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.