| Literature DB >> 21719117 |
J R Abbott1, M P Sanou, J K Coleman, J K Yamamoto.
Abstract
This review will discuss the current state of the human HIV-1 vaccine trials including the safety consideration of vaccine composition and difficulties in determining and defining protective immunity and epitopes to HIV-1. Vaccines in animal models of lentivirus infection are compared. In particular, the findings from the prototype FIV vaccine and the HIV-1 protein immunizations studies in cats are discussed, as well as the resulting research regarding a potential HIV-1 vaccine design based on evolutionarily conserved T-cell epitopes.Entities:
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Year: 2011 PMID: 21719117 PMCID: PMC4461867 DOI: 10.1016/j.vetimm.2011.06.019
Source DB: PubMed Journal: Vet Immunol Immunopathol ISSN: 0165-2427 Impact factor: 2.046