Literature DB >> 21717225

[Use of nanoparticles in ophthalomology].

I Hahn1, P Heiduschka, E Endl, N Eter.   

Abstract

Nanotechnology, the manufacture and use of structures and implements of around a few 100 nm in size, is becoming a key technology of the twenty-first century. An important element for the manufacture of nanoparticles is gold. Gold nanoparticles can be custom made and chemically modified in their size and form. Initial investigations have shown that they are physiologically non-hazardous. A potential application is in neovascular age-related macular degeneration. Gold nanoparticles of suitable dimensions introduced into newly forming blood vessels can be targeted and heated which selectively destroys these blood vessels. This principle has already been demonstrated in cultivated endothelial cells.

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Substances:

Year:  2011        PMID: 21717225     DOI: 10.1007/s00347-011-2400-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  49 in total

Review 1.  Nanomedicine in ophthalmology: the new frontier.

Authors:  Marco A Zarbin; Carlo Montemagno; James F Leary; Robert Ritch
Journal:  Am J Ophthalmol       Date:  2010-08       Impact factor: 5.258

2.  Antiangiogenic properties of gold nanoparticles.

Authors:  Priyabrata Mukherjee; Resham Bhattacharya; Ping Wang; Ling Wang; Sujit Basu; Janice A Nagy; Anthony Atala; Debabrata Mukhopadhyay; Shay Soker
Journal:  Clin Cancer Res       Date:  2005-05-01       Impact factor: 12.531

Review 3.  Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis.

Authors:  Gerald J Chader; James Weiland; Mark S Humayun
Journal:  Prog Brain Res       Date:  2009       Impact factor: 2.453

4.  Construction, gene delivery, and expression of DNA tethered nanoparticles.

Authors:  Tarl Prow; Jacob N Smith; Rhonda Grebe; Jose H Salazar; Nan Wang; Nicholas Kotov; Gerard Lutty; James Leary
Journal:  Mol Vis       Date:  2006-05-26       Impact factor: 2.367

Review 5.  [Subretinal visual implants].

Authors:  K Stingl; U Greppmaier; B Wilhelm; E Zrenner
Journal:  Klin Monbl Augenheilkd       Date:  2010-12-14       Impact factor: 0.700

6.  Treatment of experimental autoimmune uveoretinitis with intravitreal injection of tacrolimus (FK506) encapsulated in liposomes.

Authors:  Rui Zhang; Rong He; Jiang Qian; Jie Guo; Kang Xue; Yi-Fei Yuan
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-02-17       Impact factor: 4.799

Review 7.  Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy.

Authors:  Parag Aggarwal; Jennifer B Hall; Christopher B McLeland; Marina A Dobrovolskaia; Scott E McNeil
Journal:  Adv Drug Deliv Rev       Date:  2009-04-17       Impact factor: 15.470

8.  Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.

Authors:  Pooja D Jani; Nirbhai Singh; Crystal Jenkins; Swita Raghava; Yun Mo; Shivan Amin; Uday B Kompella; Balamurali K Ambati
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-05       Impact factor: 4.799

9.  Particle size-dependent organ distribution of gold nanoparticles after intravenous administration.

Authors:  Wim H De Jong; Werner I Hagens; Petra Krystek; Marina C Burger; Adriënne J A M Sips; Robert E Geertsma
Journal:  Biomaterials       Date:  2008-02-01       Impact factor: 12.479

10.  A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles.

Authors:  Xue Cai; Zack Nash; Shannon M Conley; Steven J Fliesler; Mark J Cooper; Muna I Naash
Journal:  PLoS One       Date:  2009-04-24       Impact factor: 3.240

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