Literature DB >> 21717167

Uterus didelphys with unilateral vaginal atresia: multicystic dysplastic kidney is the precursor of "renal agenesis" and the key to early diagnosis of this genital anomaly.

Ursula Kiechl-Kohlendorfer1, Theresa Geley, Kathrin Maurer, Ingmar Gassner.   

Abstract

BACKGROUND: Uterus didelphys with obstructed hemivagina (UDWOH) and ipsilateral renal agenesis is a distinct but rare entity.
OBJECTIVE: To demonstrate the association between UDWOH and a multicystic dysplastic kidney (MCDK) in neonates. To demonstrate the usefulness of sonography with vaginal fluid instillation in the early and reliable diagnosis of this genital anomaly in girls with MCDK.
MATERIALS AND METHODS: Our patients were five female neonates with a MCDK, which had been detected in utero. We performed sonography of the internal genitalia in all patients before and after filling the vagina with saline.
RESULTS: In all five girls, sonographic examination revealed uterus didelphys with obstruction of the vagina ipsilateral to the MCDK. In three girls, a dilated ureter originating from the MCDK and extending to the level of the vagina could be clearly demonstrated, with one of these including the ureteric insertion into the atretic vagina.
CONCLUSION: MCDK is key to the early diagnosis of UDWOH and will facilitate the provision of appropriate treatment. The neonatal period provides a unique opportunity for detecting uterine anomalies by sonography. An MCDK usually involutes and eventually mimics renal agenesis later in life.

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Year:  2011        PMID: 21717167     DOI: 10.1007/s00247-011-2045-z

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  29 in total

1.  Double uterus, blind hemivagina, and ipsilateral renal agenesis: 36 cases and long-term follow-up.

Authors:  G B Candiani; L Fedele; M Candiani
Journal:  Obstet Gynecol       Date:  1997-07       Impact factor: 7.661

2.  Unilateral multicystic dysplastic kidney.

Authors:  S Liebeschuetz; R Thomas
Journal:  Arch Dis Child       Date:  1997-10       Impact factor: 3.791

3.  Uterus didelphys with unilateral haematocolpos.

Authors:  K Johansen
Journal:  J Obstet Gynaecol Br Commonw       Date:  1972-01

4.  Uterine duplication, unilateral imperforate vagina, and normal kidneys.

Authors:  J Johnson; B J Hillman
Journal:  AJR Am J Roentgenol       Date:  1986-12       Impact factor: 3.959

5.  Multicystic dysplastic kidney: natural history from in utero diagnosis and postnatal followup.

Authors:  E F Avni; Y Thoua; B Lalmand; F Didier; P Droulle; C C Schulman
Journal:  J Urol       Date:  1987-12       Impact factor: 7.450

6.  Uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis: the University of Minnesota experience.

Authors:  J P Stassart; T C Nagel; K A Prem; W R Phipps
Journal:  Fertil Steril       Date:  1992-04       Impact factor: 7.329

7.  Management and outcome of patients with combined vaginal septum, bifid uterus, and ipsilateral renal agenesis (Herlyn-Werner-Wunderlich syndrome).

Authors:  Suad Gholoum; Pramod S Puligandla; Thomas Hui; Wendy Su; Elsa Quiros; Jean-Martin Laberge
Journal:  J Pediatr Surg       Date:  2006-05       Impact factor: 2.545

8.  Didelphic uterus and obstructed hemivagina with renal agenesis: case report and review of the literature.

Authors:  R K Zurawin; J E Dietrich; M J Heard; C L Edwards
Journal:  J Pediatr Adolesc Gynecol       Date:  2004-04       Impact factor: 1.814

9.  Duplication of the müllerian ducts and genitourinary malformations. Part II: analysis of malformations.

Authors:  V Gilsanz; R H Cleveland; B S Reid
Journal:  Radiology       Date:  1982-09       Impact factor: 11.105

10.  A case of unique communication between blind-ending ectopic ureter and ipsilateral hemi-hematocolpometra in uterus didelphys.

Authors:  T Shibata; K Nonomura; H Kakizaki; M Murayama; T Seki; T Koyanagi
Journal:  J Urol       Date:  1995-04       Impact factor: 7.450

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  5 in total

1.  Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist.

Authors:  Karen Psooy
Journal:  Can Urol Assoc J       Date:  2016 Jan-Feb       Impact factor: 1.862

2.  ESPR uroradiology task force and ESUR Paediatric Work Group--Imaging recommendations in paediatric uroradiology, part VI: childhood renal biopsy and imaging of neonatal and infant genital tract. Minutes from the task force session at the annual ESPR Meeting 2012 in Athens on childhood renal biopsy and imaging neonatal genitalia.

Authors:  Michael Riccabona; Maria Luisa Lobo; Ulrich Willi; Fred Avni; Beatrice Damasio; Lil-Sofie Ording-Mueller; Johan Blickman; Kassa Darge; Frederika Papadopoulou; Pierre-Hugues Vivier
Journal:  Pediatr Radiol       Date:  2014-02-20

3.  Clinical Implications of Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) Syndrome in the Prepubertal Age Group.

Authors:  Jang Hee Han; Yong Seung Lee; Young Jae Im; Sang Woon Kim; Mi-Jung Lee; Sang Won Han
Journal:  PLoS One       Date:  2016-11-18       Impact factor: 3.240

4.  Herlyn-Weber-Wunderlich syndrome with ectopic ureter in prepubertal female.

Authors:  Saurabh Garge; Deepak Bagga; Sameer Kant Acharya; Devendra Kumar Yadav; Tanvir Roshan Khan; Ram Kumar; Vinod Kumar; Srinivas Kumar; Divya Gupta; Ashish Prasad
Journal:  J Indian Assoc Pediatr Surg       Date:  2014-04

5.  A New Case of Herlyn-Werner-Wunderlich Syndrome: Uterine Didelphys with Unilateral Cervical Dysgenesis, Vaginal Agenesis, Cervical Distal Ureteral Remnant Fistula, Ureterocele, and Renal Agenesis in a Patient with Contralateral Multicystic Dysplastic Kidney.

Authors:  Jin-Hee Yu; Sa-Ra Lee; Heayeon Choi; Kun-Suk Kim; Byung-Moon Kang
Journal:  Diagnostics (Basel)       Date:  2021-12-30
  5 in total

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