| Literature DB >> 2171565 |
J McQueen1, A Jardine, J Kingdom, A Templeton, M J Whittle, J M Connell.
Abstract
We have identified two classes of membrane receptor for atrial natriuretic peptide (KD (dissociation constant) 0.2, 70.1 nmol/L) and angiotensin II (KD 1.7 nmol/L, 15.2 nmol/L) in human fetoplacental vasculature. In addition, in the isolated perfused placenta atrial natriuretic peptide inhibited the vasoconstrictor action of angiotensin II. These findings suggest that atrial natriuretic factor may regulate fetoplacental blood flow.Entities:
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Year: 1990 PMID： 2171565 DOI： 10.1093/ajh/3.8.641
Source DB: PubMed Journal: Am J Hypertens ISSN： 0895-7061 Impact factor: 2.689