AIM: Very little is known about the relationship between obsessive-compulsive disorder (OCD) and substance use disorder (SUD). The aim of this study is to compare the co-occurrence of OCD with SUD to the co-occurrence of SUD with other psychiatric disorders in a representative community sample. DESIGN: In order to examine the association of SUD and OCD, logistic regression analyses were used generating odds ratios and 95% confidence intervals for life-time prevalence and 12-month prevalence. SETTING AND PARTICIPANTS: Cross-sectional data were derived from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), a large representative sample of the Dutch population (n = 7076). MEASUREMENTS: The Composite International Diagnostic Interview (CIDI) 1.1 was used to assess Diagnostic and Statistical Manual of Mental Disorders Axis I criteria for psychiatric disorders. FINDINGS: The life-time and 12-month odds of being diagnosed with SUD in subjects with OCD are significantly higher than the odds of SUD for people without a psychiatric disorder. In men, the co-occurrence of substance dependence and OCD is significantly higher than the co-occurrence of substance dependence and other psychiatric disorders, whereas in women this co-occurrence does not differ significantly. CONCLUSIONS: The co-occurrence of substance dependence in obsessive-compulsive disorder is higher than the co-occurrence of substance dependence in other non-obsessive-compulsive disorder DSM disorders, especially in men.
AIM: Very little is known about the relationship between obsessive-compulsive disorder (OCD) and substance use disorder (SUD). The aim of this study is to compare the co-occurrence of OCD with SUD to the co-occurrence of SUD with other psychiatric disorders in a representative community sample. DESIGN: In order to examine the association of SUD and OCD, logistic regression analyses were used generating odds ratios and 95% confidence intervals for life-time prevalence and 12-month prevalence. SETTING AND PARTICIPANTS: Cross-sectional data were derived from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), a large representative sample of the Dutch population (n = 7076). MEASUREMENTS: The Composite International Diagnostic Interview (CIDI) 1.1 was used to assess Diagnostic and Statistical Manual of Mental Disorders Axis I criteria for psychiatric disorders. FINDINGS: The life-time and 12-month odds of being diagnosed with SUD in subjects with OCD are significantly higher than the odds of SUD for people without a psychiatric disorder. In men, the co-occurrence of substance dependence and OCD is significantly higher than the co-occurrence of substance dependence and other psychiatric disorders, whereas in women this co-occurrence does not differ significantly. CONCLUSIONS: The co-occurrence of substance dependence in obsessive-compulsive disorder is higher than the co-occurrence of substance dependence in other non-obsessive-compulsive disorder DSM disorders, especially in men.
Authors: Michael P Randazza; Dean McKay; Jafar Bakhshaie; Eric A Storch; Michael J Zvolensky Journal: J Obsessive Compuls Relat Disord Date: 2022-02-08 Impact factor: 1.677
Authors: Suvi Virtanen; Ralf Kuja-Halkola; Anna Sidorchuk; Lorena Fernández de la Cruz; Christian Rück; Sebastian Lundström; Jaana Suvisaari; Henrik Larsson; Paul Lichtenstein; David Mataix-Cols; Antti Latvala Journal: JAMA Netw Open Date: 2022-06-01
Authors: Marianna Mazza; Anna Losurdo; Elisa Testani; Giuseppe Marano; Marco Di Nicola; Serena Dittoni; Valentina Gnoni; Chiara Di Blasi; Nadia Mariagrazia Giannantoni; Leonardo Lapenta; Valerio Brunetti; Pietro Bria; Luigi Janiri; Salvatore Mazza; Giacomo Della Marca Journal: J Clin Sleep Med Date: 2014-01-15 Impact factor: 4.062