| Literature DB >> 2171419 |
T Suenaga1, A Hirano, J F Llena, H Ksiezak-Reding, S H Yen, D W Dickson.
Abstract
Cerebellar kuru plaques in 2 cases of Creutzfeldt-Jakob disease were studied immunohistochemically. Similar to cerebellar senile plaques in Alzheimer's disease, many kuru plaques contained ubiquitin-positive, tau-negative small granular elements, presumably representing dystrophic neurites. Our results suggest that similar mechanisms are involved in neuritic changes in cerebellar plaques in Creutzfeldt-Jakob and Alzheimer's diseases despite differences of amyloid proteins in the plaques.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2171419 DOI： 10.1002/ana.410280210
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422