Literature DB >> 21714095

Cell-free HIV-1 virucidal action by modified peptide triazole inhibitors of Env gp120.

Arangassery R Bastian1, Karyn McFadden, Caitlin Duffy, Srivats Rajagopal, Mark R Contarino, Elisabeth Papazoglou, Irwin Chaiken.   

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Year:  2011        PMID: 21714095      PMCID: PMC3517054          DOI: 10.1002/cmdc.201100177

Source DB:  PubMed          Journal:  ChemMedChem        ISSN: 1860-7179            Impact factor:   3.466


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  20 in total

1.  Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange.

Authors:  Nichole Cerutti; Barry V Mendelow; Grant B Napier; Maria A Papathanasopoulos; Mark Killick; Makobetsa Khati; Wendy Stevens; Alexio Capovilla
Journal:  J Biol Chem       Date:  2010-06-10       Impact factor: 5.157

Review 2.  Conformational changes in enveloped virus surface proteins during cell entry.

Authors:  Deborah Fass
Journal:  Adv Protein Chem       Date:  2003

3.  Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor.

Authors:  Simon Cocklin; Hosahudya Gopi; Bianca Querido; Manideepthi Nimmagadda; Syna Kuriakose; Claudia Cicala; Sandya Ajith; Sabine Baxter; James Arthos; Julio Martín-García; Irwin M Chaiken
Journal:  J Virol       Date:  2007-01-24       Impact factor: 5.103

4.  The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

Authors:  Muddegowda Umashankara; Karyn McFadden; Isaac Zentner; Arne Schön; Srivats Rajagopal; Ferit Tuzer; Syna A Kuriakose; Mark Contarino; Judith Lalonde; Ernesto Freire; Irwin Chaiken
Journal:  ChemMedChem       Date:  2010-11-08       Impact factor: 3.466

5.  The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus.

Authors:  A G Dalgleish; P C Beverley; P R Clapham; D H Crawford; M F Greaves; R A Weiss
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

6.  Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120.

Authors:  Adam Bennett; Jun Liu; Donald Van Ryk; Donald Bliss; James Arthos; Robert M Henderson; Sriram Subramaniam
Journal:  J Biol Chem       Date:  2007-06-28       Impact factor: 5.157

7.  Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120.

Authors:  Hosahudya Gopi; Simon Cocklin; Vanessa Pirrone; Karyn McFadden; Ferit Tuzer; Isaac Zentner; Sandya Ajith; Sabine Baxter; Navneet Jawanda; Fred C Krebs; Irwin M Chaiken
Journal:  J Mol Recognit       Date:  2009 Mar-Apr       Impact factor: 2.137

8.  Determination of the HIV-1 gp41 fusogenic core conformation modeled by synthetic peptides: applicable for identification of HIV-1 fusion inhibitors.

Authors:  Shuwen Liu; Qian Zhao; Shibo Jiang
Journal:  Peptides       Date:  2003-09       Impact factor: 3.750

9.  Inhibition of HIV fusion with multivalent gold nanoparticles.

Authors:  Mary-Catherine Bowman; T Eric Ballard; Christopher J Ackerson; Daniel L Feldheim; David M Margolis; Christian Melander
Journal:  J Am Chem Soc       Date:  2008-05-13       Impact factor: 15.419

10.  Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.

Authors:  Hillel Haim; Zhihai Si; Navid Madani; Liping Wang; Joel R Courter; Amy Princiotto; Aemro Kassa; Marciella DeGrace; Kathleen McGee-Estrada; Megan Mefford; Dana Gabuzda; Amos B Smith; Joseph Sodroski
Journal:  PLoS Pathog       Date:  2009-04-03       Impact factor: 6.823

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  22 in total

1.  Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.

Authors:  Lauren D Bailey; Ramalingam Venkat Kalyana Sundaram; Huiyuan Li; Caitlin Duffy; Rachna Aneja; Arangassery Rosemary Bastian; Andrew P Holmes; Kantharaju Kamanna; Adel A Rashad; Irwin Chaiken
Journal:  ACS Chem Biol       Date:  2015-10-22       Impact factor: 5.100

2.  Pharmacokinetic stability of macrocyclic peptide triazole HIV-1 inactivators alone and in liposomes.

Authors:  Rachna Aneja; Antonella Grigoletto; Aakansha Nangarlia; Adel A Rashad; Steven Wrenn; Jeffrey M Jacobson; Gianfranco Pasut; Irwin Chaiken
Journal:  J Pept Sci       Date:  2019-02-27       Impact factor: 1.905

3.  Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism.

Authors:  Valeria Cagno; Patrizia Andreozzi; Marco D'Alicarnasso; Paulo Jacob Silva; Marie Mueller; Marie Galloux; Ronan Le Goffic; Samuel T Jones; Marta Vallino; Jan Hodek; Jan Weber; Soumyo Sen; Emma-Rose Janeček; Ahmet Bekdemir; Barbara Sanavio; Chiara Martinelli; Manuela Donalisio; Marie-Anne Rameix Welti; Jean-Francois Eleouet; Yanxiao Han; Laurent Kaiser; Lela Vukovic; Caroline Tapparel; Petr Král; Silke Krol; David Lembo; Francesco Stellacci
Journal:  Nat Mater       Date:  2017-12-18       Impact factor: 43.841

4.  Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity.

Authors:  Ramalingam Venkat Kalyana Sundaram; Huiyuan Li; Lauren Bailey; Adel A Rashad; Rachna Aneja; Karl Weiss; James Huynh; Arangaserry Rosemary Bastian; Elisabeth Papazoglou; Cameron Abrams; Steven Wrenn; Irwin Chaiken
Journal:  Biochemistry       Date:  2016-01-14       Impact factor: 3.162

5.  Non-natural peptide triazole antagonists of HIV-1 envelope gp120.

Authors:  Kantharaju Kamanna; Rachna Aneja; Caitlin Duffy; Pamela Kubinski; Diogo Rodrigo Moreira; Lauren D Bailey; Karyn McFadden; Arne Schön; Andrew Holmes; Ferit Tuzer; Mark Contarino; Ernesto Freire; Irwin M Chaiken
Journal:  ChemMedChem       Date:  2012-12-13       Impact factor: 3.466

6.  Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120.

Authors:  Rachna Aneja; Adel A Rashad; Huiyuan Li; Ramalingam Venkat Kalyana Sundaram; Caitlin Duffy; Lauren D Bailey; Irwin Chaiken
Journal:  J Med Chem       Date:  2015-04-28       Impact factor: 7.446

7.  A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption.

Authors:  Ali Emileh; Ferit Tuzer; Herman Yeh; Muddegowda Umashankara; Diogo R M Moreira; Judith M Lalonde; Carole A Bewley; Cameron F Abrams; Irwin M Chaiken
Journal:  Biochemistry       Date:  2013-03-22       Impact factor: 3.162

8.  Peptide triazole inactivators of HIV-1: how do they work and what is their potential?

Authors:  Irwin Chaiken; Adel A Rashad
Journal:  Future Med Chem       Date:  2015-11-24       Impact factor: 3.808

9.  Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.

Authors:  Adel A Rashad; Li-Rui Song; Andrew P Holmes; Kriti Acharya; Shiyu Zhang; Zhi-Long Wang; Ebony Gary; Xin Xie; Vanessa Pirrone; Michele A Kutzler; Ya-Qiu Long; Irwin Chaiken
Journal:  J Med Chem       Date:  2018-06-01       Impact factor: 7.446

10.  Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter.

Authors:  Adel A Rashad; Ramalingam Venkat Kalyana Sundaram; Rachna Aneja; Caitlin Duffy; Irwin Chaiken
Journal:  J Med Chem       Date:  2015-09-11       Impact factor: 7.446

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