[Acute squamous cell carcinoma of the gallbladder: a rare cause of acute cholecystitis].

HISTORY AND ADMISSION
FINDINGS: A 54-year-old woman with signs of acute cholecystitis but no other relevant diseases was admitted into our hospital. INVESTIGATIONS: The abdominal ultrasonography showed an acute cholecystitis with possibly an abscess in the bed of the gallbladder (DD gall bladder cancer). Therefore a laparoscopy was performed which revealed a tumorous infiltrating the adjacent organs. A R1 resection was performed. DIAGNOSIS, TREATMENT AND COURSE: The histological examination revealed the rare finding of a squamous cell cancer of the gall bladder. On advice of our tumor board, chemotherapy with cisplatin and 5-flourouracil was initiated. Tumor-associated bile duct stenosis required endoscopic stent implantation. Despite the poor prognosis the disease remained stable 18 month later, with a Karnofsky index of 100 %.
CONCLUSION: Squamous cell carcinoma of the gallbladder is rare and requires a good interdisciplinary management. In an individual setting it is possible to increase survival with interdisciplinary treatment and palliative chemotherapy. © Georg Thieme Verlag KG Stuttgart · New York.