| Literature DB >> 2171337 |
V J Hunter1, L Daly, M Helms, J T Soper, A Berchuck, D L Clarke-Pearson, R C Bast.
Abstract
Fifty-four patients with advanced epithelial ovarian cancer were monitored with serial serum CA 125 levels after surgical cytoreduction and during multi-agent chemotherapy with cisplatin-containing regimens. CA 125 half-life of less than 20 days was associated with prolonged overall survival (p less than 0.015). In those patients who eventually were found to be disease-free at surgical surveillance procedures, normalization of serum CA 125 levels to less than 35 U/ml within 65 days of primary operation also suggested an improved survival (p less than 0.059).Entities:
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Year: 1990 PMID： 2171337 DOI： 10.1016/0002-9378(90)90680-6
Source DB: PubMed Journal: Am J Obstet Gynecol ISSN： 0002-9378 Impact factor: 8.661