Literature DB >> 21712285

Pacemaker clinic: an opportunity to detect silent atrial fibrillation and improve antithrombotic treatment.

Sandra Cabrera1, Jordi Mercé, Ramón de Castro, Carlos Aguirre, Ana Carmona, Mar Pinedo, Marta Salmerón, Alfredo Bardají.   

Abstract

AIMS: The prevalence of atrial fibrillation (AF) in patients with pacemakers is high, and often passes unnoticed. Our aim was to assess the use of antithrombotic treatment in this group of patients. METHODS AND
RESULTS: All patients who came to our institution to have their pacemakers checked during the year 2008 were included in this study. The atrial activity was assessed by slowing down the paced frequency if necessary, and by the analysis of atrial electrograms in atrial-based pacemakers. The appropriateness of the antithrombotic treatment was evaluated by a cardiologist. Out of 585 patients, 216 (36.9%) displayed AF at some point during the 5.5-year monitoring period (1.5-11), although only 58 (9.9%) displayed it at the time of the implant. Of these 216, 58% were men, with an average age of 80 years (76-86 years). The pacemaker was implanted in response to an atrioventricular block (AVB) in 46.3% of the cases, sinoatrial node disorder in 24.1% of the cases, and slow AF in 25.9% of the cases. The CHADS2 score was 0 points in 4.2% (9) of the cases, 1 point in 19% (41) of the cases, and ≥ 2 points in 77% (173) of the cases. Despite this, only 58.3% of the cases received anticoagulant treatment. The existence of arrhythmia at the time of implantation [odds ratio (OR) = 4.25; 95% confidence interval (95% CI), 1.72-10.51; P = 0.002] and the implantation of a pacemaker with atrioventricular synchronization (OR = 13.23; 95% CI, 2.89-60.56; P = 0.001) were associated with the use of anticoagulant treatment in those cases with CHADS2>2.
CONCLUSION: Atrial fibrillation is common in patients fitted with pacemakers. Despite the high risk of embolism, an underuse of anticoagulant treatment was observed.

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Year:  2011        PMID: 21712285     DOI: 10.1093/europace/eur160

Source DB:  PubMed          Journal:  Europace        ISSN: 1099-5129            Impact factor:   5.214


  4 in total

Review 1.  Exploring the Potential Role of Catheter Ablation in Patients with Asymptomatic Atrial Fibrillation: Should We Move away from Symptom Relief?

Authors:  Giovanni B Forleo; Luigi Di Biase; Domenico G Della Rocca; Gaetano Fassini; Luca Santini; Andrea Natale; Claudio Tondo
Journal:  J Atr Fibrillation       Date:  2013-10-31

2.  Silent atrial fibrillation is associated with P-wave duration index in patients with cardiac resynchronisation therapy.

Authors:  Abdullah Orhan Demirtas; Yahya Kemal Icen; Yurdaer Donmez; Hasan Koca; Onur Kaypakli; Mevlut Koc
Journal:  Arch Med Sci Atheroscler Dis       Date:  2019-05-27

3.  Chronic Apical and Nonapical Right Ventricular Pacing in Patients with High-Grade Atrioventricular Block: Results of the Right Pace Study.

Authors:  Carmine Muto; Valeria Calvi; Giovanni Luca Botto; Domenico Pecora; Daniele Porcelli; Alessandro Costa; Gianfranco Ciaramitaro; Riccardo Airò Farulla; Anna Rago; Raimondo Calvanese; Marco Tullio Baratto; Albino Reggiani; Massimo Giammaria; Santina Patané; Monica Campari; Sergio Valsecchi; Giampiero Maglia
Journal:  Biomed Res Int       Date:  2018-05-22       Impact factor: 3.411

4.  Continuous monitoring of sleep-disordered breathing with pacemakers: Indexes for risk stratification of atrial fibrillation and risk of stroke.

Authors:  Andrea Mazza; Maria Grazia Bendini; Massimo Leggio; Raffaele De Cristofaro; Sergio Valsecchi; Giuseppe Boriani
Journal:  Clin Cardiol       Date:  2020-11-12       Impact factor: 2.882

  4 in total

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