Literature DB >> 2171206

A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication.

E M Coccia1, G Romeo, A Nissim, G Marziali, R Albertini, E Affabris, A Battistini, G Fiorucci, R Orsatti, G B Rossi.   

Abstract

Treatment of cells with interferons (IFNs) induces resistance to virus infection. The 2'-5'oligo A (2-5A) synthetase/RNase L is one of the pathways leading to translation inhibition induced by IFN treatment. A murine cDNA encoding the 43-kDa 2-5A synthetase was cloned and sequenced. NIH-3T3 cell clones transfected with this cDNA expressed the enzymatic activity to various extents and exhibited resistance to encephalomyocarditis virus (EMCV) but not to vesicular stomatitis virus replication. The specific resistance to EMCV can be attributed to 2-5A synthetase.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2171206     DOI： 10.1016/0042-6822(90)90292-y

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  28 in total

1.  Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.

Authors:  Helle Kristiansen; Christina A Scherer; Maralee McVean; Shawn P Iadonato; Susanne Vends; Karthiga Thavachelvam; Thomas B Steffensen; Kristy A Horan; Thomas Kuri; Friedemann Weber; Søren R Paludan; Rune Hartmann
Journal:  J Virol       Date:  2010-09-15       Impact factor: 5.103

2.  A mammalian 2-5A system functions as an antiviral pathway in transgenic plants.

Authors:  A Mitra; D W Higgins; W G Langenberg; H Nie; D N Sengupta; R H Silverman
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

3.  Posttranscriptional regulation of beta interferon expression in erythroid Friend cells treated with gamma interferon.

Authors:  G Marziali; G Fiorucci; E M Coccia; Z Percario; J Raber; A Battistini; G B Rossi; E Affabris; G Romeo
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

4.  Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency.

Authors:  Erik S Barton; Mary L Lutzke; Rosemary Rochford; Herbert W Virgin
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

5.  The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus.

Authors:  Miki Ida-Hosonuma; Takuya Iwasaki; Tomoki Yoshikawa; Noriyo Nagata; Yuko Sato; Tetsutaro Sata; Mitsutoshi Yoneyama; Takashi Fujita; Choji Taya; Hiromichi Yonekawa; Satoshi Koike
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

6.  Protection from lethal coxsackievirus-induced pancreatitis by expression of gamma interferon.

Authors:  M S Horwitz; T Krahl; C Fine; J Lee; N Sarvetnick
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

7.  Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth.

Authors:  E F Meurs; Y Watanabe; S Kadereit; G N Barber; M G Katze; K Chong; B R Williams; A G Hovanessian
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

8.  Gamma interferon is a major suppressive factor produced by activated human peripheral blood lymphocytes that is able to inhibit foamy virus-induced cytopathic effects.

Authors:  V Falcone; M Schweizer; A Toniolo; D Neumann-Haefelin; A Meyerhans
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

9.  RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cells.

Authors:  C Martinand; C Montavon; T Salehzada; M Silhol; B Lebleu; C Bisbal
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

10.  Suppressor of cytokine signalling protein SOCS1 and UBP43 regulate the expression of type I interferon-stimulated genes in human microvascular endothelial cells infected with Rickettsia conorii.

Authors:  Punsiri M Colonne; Abha Sahni; Sanjeev K Sahni
Journal:  J Med Microbiol       Date:  2013-04-04       Impact factor: 2.472
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.