Literature DB >> 21709866

Protein stability in an ionic liquid milieu: on the use of differential scanning fluorimetry.

João V Rodrigues1, Vesna Prosinecki, Isabel Marrucho, Luís Paulo N Rebelo, Cláudio M Gomes.   

Abstract

Protein stability is a major bottleneck in the biotechnological application of ionic liquid-containing solvents, either in the frame of biocatalysis or protein storage. Herein, differential scanning fluorimetry was successfully implemented as a high throughput method to fast scan the impact of a number of cholinium-based ionic liquids on the stability of proteins.

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Year:  2011        PMID： 21709866     DOI： 10.1039/c1cp21187k

Source DB:  PubMed          Journal:  Phys Chem Chem Phys        ISSN： 1463-9076            Impact factor:   3.676


  10 in total

1.  Guided inquiry activity linking thermodynamic parameters of protein unfolding to structure using differential scanning fluorimetry data in the biophysical chemistry classroom.

Authors:  Patrick Emery; Ellen J Yezierski; Richard C Page
Journal:  Biochem Mol Biol Educ       Date:  2018-12-22       Impact factor: 1.160

2.  Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active-site substitutions.

Authors:  Maximilian C C J C Ebert; Krista L Morley; Jordan P Volpato; Andreea R Schmitzer; Joelle N Pelletier
Journal:  Protein Sci       Date:  2014-12-26       Impact factor: 6.725

Review 3.  Ionic liquids as biocompatible stabilizers of proteins.

Authors:  Mouhamad Reslan; Veysel Kayser
Journal:  Biophys Rev       Date:  2018-03-06

4.  Protein remains stable at unusually high temperatures when solvated in aqueous mixtures of amino acid based ionic liquids.

Authors:  Guillaume Chevrot; Eudes Eterno Fileti; Vitaly V Chaban
Journal:  J Mol Model       Date:  2016-10-05       Impact factor: 1.810

5.  Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays.

Authors:  Shenzhen Huang; Xiang Wang; Guifeng Lin; Jie Cheng; Xiuli Chen; Weining Sun; Rong Xiang; Yamei Yu; Linli Li; Shengyong Yang
Journal:  RSC Adv       Date:  2019-03-22       Impact factor: 4.036

6.  Notable Stabilization of α-Chymotrypsin by the Protic Ionic Additive, [ch][dhp]: Calorimetric Evidence for a Fine Enthalpy/Entropy Balance.

Authors:  Sophio Uchaneishvili; Maya Makharadze; Mikhael Shushanyan; Rudi van Eldik; Dimitri E Khoshtariya
Journal:  Int Sch Res Notices       Date:  2014-09-07

Review 7.  Proteins in Ionic Liquids: Current Status of Experiments and Simulations.

Authors:  Christian Schröder
Journal:  Top Curr Chem (Cham)       Date:  2017-02-07

Review 8.  Effects of Ionic Liquids on Metalloproteins.

Authors:  Aashka Y Patel; Keertana S Jonnalagadda; Nicholas Paradis; Timothy D Vaden; Chun Wu; Gregory A Caputo
Journal:  Molecules       Date:  2021-01-19       Impact factor: 4.411

9.  Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles.

Authors:  Xuan Lin; Yanli Yang; Shuai Li; Yanmin Song; Guanghui Ma; Zhiguo Su; Songping Zhang
Journal:  RSC Adv       Date:  2019-05-07       Impact factor: 3.361

10.  Differential Scanning Fluorimetry provides high throughput data on silk protein transitions.

Authors:  Fritz Vollrath; Nick Hawkins; David Porter; Chris Holland; Maxime Boulet-Audet
Journal:  Sci Rep       Date:  2014-07-09       Impact factor: 4.379
  10 in total

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