Literature DB >> 21709763

New Nanomedicine Approaches Using Gold-thioguanine Nanoconjugates as Metallo-ligands.

Lee Sleightholm1, Ajit Zambre, Nripen Chanda, Zahra Afrasiabi, Kattesh Katti, Raghuraman Kannan.   

Abstract

Gold-thioguanine nanoconjugates (AuNP-TG) of size 3-4 nm were synthesized and the ratio between gold and 6-Thioguanine (TG) was estimated as ~1:1.5 using a cyanide digestion method and confirmed by flame atomic absorption spectroscopic analysis. AuNP-TG constructs showed high in vitro stability under different pH conditions and biologically relevant solutions for a period of 24 hours. Reaction of AuNP-TG with europium or platinum salts resulted in the formation of organized self-assembled metallo-networks.

Entities:  

Year:  2011        PMID： 21709763      PMCID： PMC3121184          DOI： 10.1016/j.ica.2011.01.065

Source DB:  PubMed          Journal:  Inorganica Chim Acta        ISSN： 0020-1693            Impact factor:   2.545


  33 in total

Review 1.  Molecular biology and anticancer drug discovery.

Authors:  John S Lazo
Journal:  Prog Mol Biol Transl Sci       Date:  2010       Impact factor: 3.622

2.  Theoretical study of the guanine --> 6-thioguanine substitution in duplexes, triplexes, and tetraplexes.

Authors:  Nad'a Spacková; Elena Cubero; Jirí Sponer; Modesto Orozco
Journal:  J Am Chem Soc       Date:  2004-11-10       Impact factor: 15.419

3.  An effective strategy for the synthesis of biocompatible gold nanoparticles using cinnamon phytochemicals for phantom CT imaging and photoacoustic detection of cancerous cells.

Authors:  Nripen Chanda; Ravi Shukla; Ajit Zambre; Swapna Mekapothula; Rajesh R Kulkarni; Kavita Katti; Kiran Bhattacharyya; Genevieve M Fent; Stan W Casteel; Evan J Boote; John A Viator; Anandhi Upendran; Raghuraman Kannan; Kattesh V Katti
Journal:  Pharm Res       Date:  2010-09-25       Impact factor: 4.200

Review 4.  6-thioguanine in the treatment of psoriasis: a case report and literature review.

Authors:  Daniel W Sherer; Mark G Lebwohl
Journal:  J Cutan Med Surg       Date:  2002-05-13       Impact factor: 2.092

5.  Possible carcinogenic effect of 6-mercaptopurine on bone marrow stem cells: relation to thiopurine metabolism.

Authors:  J Bo; H Schrøder; J Kristinsson; B Madsen; C Szumlanski; R Weinshilboum; J B Andersen; K Schmiegelow
Journal:  Cancer       Date:  1999-09-15       Impact factor: 6.860

Review 6.  Towards a targeted multi-drug delivery approach to improve therapeutic efficacy in breast cancer.

Authors:  Bin Wang; Jenna M Rosano; Rabe'e Cheheltani; Mohan P Achary; Mohammad F Kiani
Journal:  Expert Opin Drug Deliv       Date:  2010-10       Impact factor: 6.648

7.  Low concentrations of cytosine arabinoside, 6-thioguanine, actinomycin-D and aclacinomycin A stimulates the differentiation of normal human marrow myeloid progenitor cells.

Authors:  H T Hassan; J K Rees
Journal:  Med Oncol Tumor Pharmacother       Date:  1989

8.  Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity.

Authors:  Nripen Chanda; Vijaya Kattumuri; Ravi Shukla; Ajit Zambre; Kavita Katti; Anandhi Upendran; Rajesh R Kulkarni; Para Kan; Genevieve M Fent; Stan W Casteel; C Jeffrey Smith; Evan Boote; J David Robertson; Cathy Cutler; John R Lever; Kattesh V Katti; Raghuraman Kannan
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-21       Impact factor: 11.205

9.  Biodistribution of maltose and gum arabic hybrid gold nanoparticles after intravenous injection in juvenile swine.

Authors:  Genevieve M Fent; Stan W Casteel; Dae Young Kim; Raghuraman Kannan; Kavita Katti; Nripen Chanda; Kattesh Katti
Journal:  Nanomedicine       Date:  2009-06       Impact factor: 5.307

10.  Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery.

Authors:  Mani Prabaharan; Jamison J Grailer; Srikanth Pilla; Douglas A Steeber; Shaoqin Gong
Journal:  Biomaterials       Date:  2009-08-12       Impact factor: 12.479
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  2 in total

1.  Species-Specific in vitro and in vivo Evaluation of Toxicity of Silver Nanoparticles Stabilized with Gum Arabic Protein.

Authors:  Joana S Maziero; Velaphi C Thipe; Sizue O Rogero; Adriana K Cavalcante; Kelme C Damasceno; Matheus B Ormenio; Gisela A Martini; Jorge G S Batista; William Viveiros; Kavita K Katti; Alice Raphael Karikachery; DarshaKumar Dhurvas Mohandoss; Rashmi DarshaKumar Dhurvas; Mohanavelu Nappinnai; José R Rogero; Ademar B Lugão; Kattesh V Katti
Journal:  Int J Nanomedicine       Date:  2020-10-02

Review 2.  Advances in Thiopurine Drug Delivery: The Current State-of-the-Art.

Authors:  Ahmed B Bayoumy; Femke Crouwel; Nripen Chanda; Timothy H J Florin; Hans J C Buiter; Chris J J Mulder; Nanne K H de Boer
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2021-09-06       Impact factor: 2.441
  2 in total

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