| Literature DB >> 21708464 |
K Satish1, M V P S Vishnuvardhan, V Lakshma Nayak, G Srihari, M Subrahamanyam, T Prabhakar Rao, S Ramakrishna, K Ravikumar, B Sridhar, M Marthanda Murthy.
Abstract
Two new diterpenoid quinonemethides (1 and 2) along with two known compounds (3 and 4) were isolated from the hexane and ethyl acetate extracts of root nodules of Pygmacopremna herbacea. The structures of the new compounds were established by spectroscopic data interpretation. Single crystal X-ray diffraction analysis confirmed the structure of 1. The cytotoxic activities of these compounds were evaluated against A 549, HEPG2, MCF-7, PC-3 and HELA cancer cell lines. Compounds 4, 2 and 1 were shown very good cytotoxic activity.Entities:
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Year: 2011 PMID： 21708464 DOI： 10.1016/j.bmcl.2011.05.109
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823