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Literature DB >> 21708316

The balance between excitation and inhibition and functional sensory processing in the somatosensory cortex.

Abstract

The balance between excitation and inhibition (E/I balance) is tightly regulated in adult cortices to maintain proper nervous system function. Disturbed E/I balance is associated with numerous neuropsychological disorders, such as autism, epilepsy and schizophrenia. The present review will discuss aspects of Hebbian and homeostatic mechanisms regulating excitatory and inhibitory balance related to sensory processing in somatosensory cortex of rodents. Additionally, changes in the E/I balance during sensory manipulation will be discussed.

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Year: 2011 PMID： 21708316 DOI： 10.1016/B978-0-12-385198-7.00012-6

Source DB: PubMed Journal: Int Rev Neurobiol ISSN： 0074-7742 Impact factor: 3.230

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Cited

23 in total

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The balance between excitation and inhibition and functional sensory processing in the somatosensory cortex.

Review 1. Optogenetics enlightens neuroscience drug discovery.

2. Multisensory temporal function and EEG complexity in patients with epilepsy and psychogenic nonepileptic events.

3. Vibrotactile discriminative capacity is impacted in a digit-specific manner with concurrent unattended hand stimulation.

4. Biphasic modulation of parallel fibre synaptic transmission by co-activation of presynaptic GABAA and GABAB receptors in mice.

5. Dendritic arborization and spine dynamics are abnormal in the mouse model of MECP2 duplication syndrome.

6. Enhancement of postsynaptic GABAA and extrasynaptic NMDA receptor-mediated responses in the barrel cortex of Mecp2-null mice.

7. On the Complexity of Resting State Spiking Activity in Monkey Motor Cortex.

8. Reduced GABA and altered somatosensory function in children with autism spectrum disorder.

9. Time-lapse electrical recordings of single neurons from the mouse neocortex.

10. Altered tactile sensitivity in children with attention-deficit hyperactivity disorder.