Literature DB >> 21707349

Human genome project and sickle cell disease.

Brenda J Norman1, Sheila D Miller.   

Abstract

Sickle cell disease is one of the most common genetic blood disorders in the United States that affects 1 in every 375 African Americans. Sickle cell disease is an inherited condition caused by abnormal hemoglobin in the red blood cells. The Human Genome Project has provided valuable insight and extensive research advances in the understanding of the human genome and sickle cell disease. Significant progress in genetic knowledge has led to an increase in the ability for researchers to map and sequence genes for diagnosis, treatment, and prevention of sickle cell disease and other chronic illnesses. This article explores some of the recent knowledge and advances about sickle cell disease and the Human Genome Project.

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Year:  2011        PMID: 21707349     DOI: 10.1080/19371918.2011.579488

Source DB:  PubMed          Journal:  Soc Work Public Health        ISSN: 1937-190X


  3 in total

Review 1.  Psychological Predictors of Pain in Children and Adolescents With Sickle Cell Disease: A Scoping Review.

Authors:  Clare Donohoe; Ellen Lavoie Smith
Journal:  J Pediatr Oncol Nurs       Date:  2018-12-19       Impact factor: 1.636

2.  A call for policy action in sub-Saharan Africa to rethink diagnostics for pregnancy affected by sickle cell disease: differential views of medical doctors, parents and adult patients predict value conflicts in Cameroon.

Authors:  Ambroise Wonkam; Samia Hurst
Journal:  OMICS       Date:  2014-04-22

Review 3.  Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.

Authors:  Kenneth B Gagnon; Eric Delpire
Journal:  Am J Physiol Cell Physiol       Date:  2013-01-16       Impact factor: 4.249

  3 in total

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