Literature DB >> 21706192

Warfarin anticoagulation: a survey of patients' knowledge of their treatment.

S M Moran1, N Fitzgerald, M Pope, M Madden, C J Vaughan.   

Abstract

INTRODUCTION: Warfarin is used for the treatment of thromboembolic disease. It requires careful and sustained monitoring due to its narrow therapeutic index and potentially life-threatening complications. Patient education and knowledge is, therefore, vital. AIMS: To assess, in a specialised anticoagulation clinic, the extent of patients' knowledge of their warfarin treatment.
METHODS: Ethical approval was obtained. All patients, aged over 18 years, attending our anticoagulation clinic during our study period were asked to participate.
RESULTS: We enrolled 181 patients, 47.9% of respondents were unaware of any potential drug interactions, 57.7% of patients were unaware of any potential side effects, 20% of patients had experienced side effects, 10.9% of patients had been hospitalised due to side effects, 58% of which were due to Haemorrhage and 79% of patients kept a personal record of their INR.
CONCLUSIONS: Patients' understanding of warfarin treatment was poor, despite their high level of compliance.

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Year:  2011        PMID: 21706192     DOI: 10.1007/s11845-011-0726-0

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  11 in total

1.  American Heart Association/American College of Cardiology Foundation guide to warfarin therapy.

Authors:  Jack Hirsh; Valentin Fuster; Jack Ansell; Jonathan L Halperin
Journal:  J Am Coll Cardiol       Date:  2003-05-07       Impact factor: 24.094

2.  Poor compliance is a major factor in unstable outpatient control of anticoagulant therapy.

Authors:  S Kumar; J R Haigh; L E Rhodes; S Peaker; J A Davies; B E Roberts; M P Feely
Journal:  Thromb Haemost       Date:  1989-09-29       Impact factor: 5.249

3.  Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy.

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Journal:  Am J Med       Date:  1989-08       Impact factor: 4.965

4.  National surveillance of emergency department visits for outpatient adverse drug events.

Authors:  Daniel S Budnitz; Daniel A Pollock; Kelly N Weidenbach; Aaron B Mendelsohn; Thomas J Schroeder; Joseph L Annest
Journal:  JAMA       Date:  2006-10-18       Impact factor: 56.272

5.  Incidence and preventability of adverse drug events among older persons in the ambulatory setting.

Authors:  Jerry H Gurwitz; Terry S Field; Leslie R Harrold; Jeffrey Rothschild; Kristin Debellis; Andrew C Seger; Cynthia Cadoret; Leslie S Fish; Lawrence Garber; Michael Kelleher; David W Bates
Journal:  JAMA       Date:  2003-03-05       Impact factor: 56.272

6.  Warfarin: a case history in pharmacogenetics.

Authors:  A M Hall; M R Wilkins
Journal:  Heart       Date:  2005-05       Impact factor: 5.994

7.  Drug interaction with coumarin derivative anticoagulants. Standing Advisory Committee for Haematology of the Royal College of Pathologists.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1982-07-24

8.  Trial of different intensities of anticoagulation in patients with prosthetic heart valves.

Authors:  J N Saour; J O Sieck; L A Mamo; A S Gallus
Journal:  N Engl J Med       Date:  1990-02-15       Impact factor: 91.245

9.  Gains and losses of warfarin therapy as performed in an anticoagulation clinic.

Authors:  A M Njaastad; U Abildgaard; J F Lassen
Journal:  J Intern Med       Date:  2006-03       Impact factor: 8.989

10.  Relationship between patients' warfarin knowledge and anticoagulation control.

Authors:  Elaine Othilia Y L Tang; Cemen S M Lai; Kenneth K C Lee; Raymond S M Wong; Gregory Cheng; Thomas Y K Chan
Journal:  Ann Pharmacother       Date:  2003-01       Impact factor: 3.154

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  2 in total

1.  Warfarin and topical miconazole: the potential for a clinically significant interaction.

Authors:  C C Ufondu; P Ferrins; A Cushen; J Quinn
Journal:  Ir J Med Sci       Date:  2012-11-01       Impact factor: 1.568

2.  Do herbal formulas influence the international normalized ratio of patients taking warfarin? A retrospective study.

Authors:  Hsu-Yuan Lu; Seung-Yeon Cho; Seong-Uk Park; Woo-Sang Jung; Sang-Kwan Moon; Jung-Mi Park; Chang-Nam Ko
Journal:  Evid Based Complement Alternat Med       Date:  2015-03-10       Impact factor: 2.629

  2 in total

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