Literature DB >> 21703840

Immune responses in the skin in old age.

Milica Vukmanovic-Stejic1, Malcolm H A Rustin, Janko Nikolich-Zugich, Arne N Akbar.   

Abstract

A marked increase in the susceptibility to cutaneous infections and malignancies has been observed in older humans indicating that cutaneous immunity becomes defective with age. In this review we will focus on recent developments in the understanding of age-related changes in immune function of the skin with a particular emphasis on how alterations in the interaction between cells involved in innate and adaptive immunity leads to decreased cutaneous antigen-specific T cell immunosurveillance.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21703840     DOI： 10.1016/j.coi.2011.05.008

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  23 in total

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Review 2.  Natural and sun-induced aging of human skin.

Authors:  Laure Rittié; Gary J Fisher
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Review 5.  Understanding immunosenescence to improve responses to vaccines.

Authors:  Jörg J Goronzy; Cornelia M Weyand
Journal:  Nat Immunol       Date:  2013-04-18       Impact factor: 25.606

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Review 7.  Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.

Authors:  Janko Nikolich-Žugich
Journal:  J Immunol       Date:  2014-09-15       Impact factor: 5.422

8.  The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.

Authors:  Milica Vukmanovic-Stejic; Daisy Sandhu; Judith A Seidel; Neil Patel; Toni O Sobande; Elaine Agius; Sarah E Jackson; Judilyn Fuentes-Duculan; Mayte Suárez-Fariñas; Neil A Mabbott; Katie E Lacy; Graham Ogg; Frank O Nestle; James G Krueger; Malcolm H A Rustin; Arne N Akbar
Journal:  J Invest Dermatol       Date:  2015-03-03       Impact factor: 8.551

9.  Investigation of the cutaneous response to recall antigen in humans in vivo.

Authors:  A N Akbar; J R Reed; K E Lacy; S E Jackson; M Vukmanovic-Stejic; M H A Rustin
Journal:  Clin Exp Immunol       Date:  2013-08       Impact factor: 4.330

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Authors:  Michelle L McCully; Paul J Collins; Timothy R Hughes; Christopher P Thomas; Jaak Billen; Valerie B O'Donnell; Bernhard Moser
Journal:  J Immunol       Date:  2015-05-22       Impact factor: 5.422
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