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Literature DB >> 21701752

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor.

Marc Vendrell¹, Gaddamanugu Gopi Krishna, Krishna Kanta Ghosh, Duanting Zhai, Jun-Seok Lee, Qing Zhu, Yin Hoe Yau, Susana Geifman Shochat, Hyori Kim, Junho Chung, Young-Tae Chang.

Abstract

The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

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Year: 2011 PMID： 21701752 DOI： 10.1039/c1cc11774b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

12 in total

1. Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging.

Authors: Lorena Mendive-Tapia; Ramon Subiros-Funosas; Can Zhao; Fernando Albericio; Nick D Read; Rodolfo Lavilla; Marc Vendrell
Journal: Nat Protoc Date: 2017-07-13 Impact factor: 13.491

2. Interaction of BODIPY dyes with bovine serum albumin: a case study on the aggregation of a click-BODIPY dye.

Authors: Laramie P Jameson; Nicholas W Smith; Onofrio Annunziata; Sergei V Dzyuba
Journal: Phys Chem Chem Phys Date: 2016-05-13 Impact factor: 3.676

3. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.

Authors: Ashley M Laughney; Eunha Kim; Melissa M Sprachman; Miles A Miller; Rainer H Kohler; Katy S Yang; James D Orth; Timothy J Mitchison; Ralph Weissleder
Journal: Sci Transl Med Date: 2014-11-05 Impact factor: 17.956

4. Multicomponent reactions for de novo synthesis of BODIPY probes: in vivo imaging of phagocytic macrophages.

Authors: Ana Vázquez-Romero; Nicola Kielland; María J Arévalo; Sara Preciado; Richard J Mellanby; Yi Feng; Rodolfo Lavilla; Marc Vendrell
Journal: J Am Chem Soc Date: 2013-10-16 Impact factor: 15.419

5. A highly selective fluorescent probe for direct detection and isolation of mouse embryonic stem cells.

Authors: Yogeswari Chandran; Nam-Young Kang; Sung-Jin Park; Samira Husen Alamudi; Jun-Young Kim; Srikanta Sahu; Dongdong Su; Jungyeol Lee; Marc Vendrell; Young-Tae Chang
Journal: Bioorg Med Chem Lett Date: 2015-06-16 Impact factor: 2.823

6. Development of background-free tame fluorescent probes for intracellular live cell imaging.

Authors: Samira Husen Alamudi; Rudrakanta Satapathy; Jihyo Kim; Dongdong Su; Haiyan Ren; Rajkumar Das; Lingna Hu; Enrique Alvarado-Martínez; Jung Yeol Lee; Christian Hoppmann; Eduardo Peña-Cabrera; Hyung-Ho Ha; Hee-Sung Park; Lei Wang; Young-Tae Chang
Journal: Nat Commun Date: 2016-06-20 Impact factor: 14.919

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor.

1. Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging.

2. Interaction of BODIPY dyes with bovine serum albumin: a case study on the aggregation of a click-BODIPY dye.

3. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.

4. Multicomponent reactions for de novo synthesis of BODIPY probes: in vivo imaging of phagocytic macrophages.

5. A highly selective fluorescent probe for direct detection and isolation of mouse embryonic stem cells.

6. Development of background-free tame fluorescent probes for intracellular live cell imaging.

7. A fluorescent activatable probe for imaging intracellular Mg²⁺ .

8. Solid-phase fluorescent BODIPY-peptide synthesis via in situ dipyrrin construction.

9. Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue.

10. A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase.