Literature DB >> 21701337

Extensive percutaneous aponeurotomy and lipografting: a new treatment for Dupuytren disease.

Steven E R Hovius1, Hester J Kan, Xander Smit, Ruud W Selles, Eufimiano Cardoso, Roger K Khouri.   

Abstract

BACKGROUND: Surgical resection of Dupuytren contracture is fraught with morbidity and prolonged recovery. This article introduces a novel minimally invasive alternative for Dupuytren disease and its outcome.
METHODS: The procedure consists of an extensive percutaneous aponeurotomy that completely disintegrates the cord and separates it from the dermis. Subsequently, the resultant loosened structure is grafted with autologous lipoaspirate. After 1 week of postoperative extension splinting, patients are allowed normal hand use and are advised to use night splints for 3 to 6 months. The authors treated and report on their experience with 91 patients (99 hands) operated on in Miami and Rotterdam; from 50 patients, the authors report on goniometry (average follow-up, 44 weeks).
RESULTS: The contracture from the proximal interphalangeal joint improved significantly from 61 degrees to 27 degrees, and contracture from the metacarpophalangeal joint improved from 37 degrees to -5 degrees. Ninety-four percent of patients returned to normal use of the hand within 2 to 4 weeks and 95 percent were very satisfied with the result. No new scars were added, and a supple palmar fat pad was mostly restored. Complications were digital nerve injury in one patient, postoperative wound infection in one patient, and complex regional pain syndrome in four patients.
CONCLUSIONS: This new minimally invasive technique shortens recovery time, adds to the deficient subcutaneous fat, and leads to scarless supple skin. By its ability to treat multiple rays, it addresses the abnormality in the entire hand. The procedure is safe and effective, especially for primary cases. Currently, comparative prospective randomized studies are in process to fully determine its role in the treatment of Dupuytren contracture. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.(Figure is included in full-text article.).

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Year:  2011        PMID: 21701337     DOI: 10.1097/PRS.0b013e31821741ba

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  15 in total

1.  Current concepts in Dupuytren's disease.

Authors:  Steven Lo; Mark Pickford
Journal:  Curr Rev Musculoskelet Med       Date:  2013-03

Review 2.  Dupuytren's disease: current state of the art.

Authors:  Mark Henry
Journal:  Hand (N Y)       Date:  2014-03

Review 3.  Fat Grafting for Hand Rejuvenation.

Authors:  Christopher J Conlon; Amjed Abu-Ghname; Matthew J Davis; Kausar Ali; Sebastian J Winocour; Michael L Eisemann; Julian Winocour
Journal:  Semin Plast Surg       Date:  2020-02-15       Impact factor: 2.314

Review 4.  Optimal functional outcome measures for assessing treatment for Dupuytren's disease: a systematic review and recommendations for future practice.

Authors:  Catherine Ball; Anna L Pratt; Jagdeep Nanchahal
Journal:  BMC Musculoskelet Disord       Date:  2013-04-10       Impact factor: 2.362

5.  Recent Surgical and Medical Advances in the Treatment of Dupuytren's Disease - A Systematic Review of the Literature.

Authors:  Mafi R; Hindocha S; Khan W
Journal:  Open Orthop J       Date:  2012-02-23

6.  Autologous Fat Transfer in Secondary Carpal Tunnel Release.

Authors:  Natalia Ewa Krześniak; Bartłomiej H Noszczyk
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-06-05

Review 7.  What are we measuring? A critique of range of motion methods currently in use for Dupuytren's disease and recommendations for practice.

Authors:  Anna L Pratt; Catherine Ball
Journal:  BMC Musculoskelet Disord       Date:  2016-01-13       Impact factor: 2.362

8.  Use of human fat grafting in the prevention of perineural adherence: Experimental study in athymic mouse.

Authors:  Mario Cherubino; Igor Pellegatta; Alessandro Crosio; Luigi Valdatta; Stefano Geuna; Rosalba Gornati; Pierluigi Tos
Journal:  PLoS One       Date:  2017-04-26       Impact factor: 3.240

Review 9.  Surgery for Dupuytren's contracture of the fingers.

Authors:  Jeremy N Rodrigues; Giles W Becker; Cathy Ball; Weiya Zhang; Henk Giele; Jonathan Hobby; Anna L Pratt; Tim Davis
Journal:  Cochrane Database Syst Rev       Date:  2015-12-09

10.  Autologous fat transfer with in-situ mediation (AIM): a novel and compliant method of adult mesenchymal stem cell therapy.

Authors:  Allan Y Wu; David M Morrow
Journal:  J Transl Med       Date:  2013-05-31       Impact factor: 5.531

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