Literature DB >> 21699898

Oxaliplatin uses JNK to restore TRAIL sensitivity in cancer cells through Bcl-xL inactivation.

Joshua E Allen, Wafik S El-Deiry.   

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Year:  2011        PMID: 21699898     DOI: 10.1053/j.gastro.2011.06.026

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


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  7 in total

1.  Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation.

Authors:  Weiyang He; Qiong Wang; Jennings Xu; Xiuling Xu; Mabel T Padilla; Guosheng Ren; Xin Gou; Yong Lin
Journal:  Autophagy       Date:  2012-10-10       Impact factor: 16.016

2.  Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10.

Authors:  Joshua E Allen; Varun V Prabhu; Mala Talekar; A Pieter J van den Heuvel; Bora Lim; David T Dicker; Jennifer L Fritz; Adam Beck; Wafik S El-Deiry
Journal:  Cancer Res       Date:  2015-02-13       Impact factor: 12.701

3.  Downregulation of NPM expression by Her-2 reduces resistance of gastric cancer to oxaliplatin.

Authors:  Zhenni Sun; Lu Yue; Zan Shen; Yong Li; Aihua Sui; Tianjun Li; Qian Tang; Ruyong Yao; Yongning Sun
Journal:  Oncol Lett       Date:  2017-02-13       Impact factor: 2.967

4.  Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.

Authors:  Joshua E Allen; Gabriel Krigsfeld; Luv Patel; Patrick A Mayes; David T Dicker; Gen Sheng Wu; Wafik S El-Deiry
Journal:  Mol Cancer       Date:  2015-05-01       Impact factor: 27.401

5.  DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer.

Authors:  Zheng Wang; Yi Li; Rui Mao; Yu Zhang; Jun Wen; Qian Liu; Yanjun Liu; Tongtong Zhang
Journal:  Cell Death Dis       Date:  2022-02-14       Impact factor: 8.469

Review 6.  Genetic and biological hallmarks of colorectal cancer.

Authors:  Jiexi Li; Xingdi Ma; Deepavali Chakravarti; Shabnam Shalapour; Ronald A DePinho
Journal:  Genes Dev       Date:  2021-06       Impact factor: 11.361

Review 7.  Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL).

Authors:  Mohammed I Y Elmallah; Olivier Micheau
Journal:  Mar Drugs       Date:  2015-11-13       Impact factor: 5.118

  7 in total

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