Literature DB >> 21699874

Assessing electrocardiographic data quality and possible replacement of pharmacologic positive control in thorough QT/QTc studies by investigations of drug-free QTc stability.

Marek Malik1, Joanne Zhang, Lars Johannesen, Katerina Hnatkova, Christine Garnett.   

Abstract

Mesh：

Substances：

Year:  2011        PMID： 21699874     DOI： 10.1016/j.hrthm.2011.06.016

Source DB:  PubMed          Journal:  Heart Rhythm        ISSN： 1547-5271            Impact factor:   6.343


× No keyword cloud information.
  9 in total

1.  The thorough QT study: Is its demise on the horizon?

Authors:  Philip T Sager; Peter Kowey
Journal:  Ann Noninvasive Electrocardiol       Date:  2014-01-08       Impact factor: 1.468

2.  Implications of the IQ-CSRC Prospective Study: Time to Revise ICH E14.

Authors:  Borje Darpo; Christine Garnett; James Keirns; Norman Stockbridge
Journal:  Drug Saf       Date:  2015-09       Impact factor: 5.606

Review 3.  Early QT assessment--how can our confidence in the data be improved?

Authors:  Borje Darpo; Christine Garnett
Journal:  Br J Clin Pharmacol       Date:  2013-11       Impact factor: 4.335

Review 4.  Dealing with global safety issues : was the response to QT-liability of non-cardiac drugs well coordinated?

Authors:  Norman Stockbridge; Joel Morganroth; Rashmi R Shah; Christine Garnett
Journal:  Drug Saf       Date:  2013-03       Impact factor: 5.606

5.  Baseline correction in parallel thorough QT studies.

Authors:  Joanne Zhang; Qianyu Dang; Marek Malik
Journal:  Drug Saf       Date:  2013-06       Impact factor: 5.606

6.  Use of continuous ECG for improvements in assessing the standing response as a positive control for QT prolongation.

Authors:  Anthony A Fossa; Meijian Zhou; Nuala Brennan; Patrick Round; John Ford
Journal:  Ann Noninvasive Electrocardiol       Date:  2013-09-09       Impact factor: 1.468

7.  Electrocardiographic data quality in thorough QT/QTc studies.

Authors:  Lars Johannesen; Christine Garnett; Marek Malik
Journal:  Drug Saf       Date:  2014-03       Impact factor: 5.606

8.  Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity.

Authors:  Georg Ferber; Sara Fernandes; Jörg Täubel
Journal:  J Clin Pharmacol       Date:  2017-08-17       Impact factor: 3.126

9.  Implications of Individual QT/RR Profiles-Part 2: Zero QTc/RR Correlations Do Not Prove QTc Correction Accuracy in Studies of QTc Changes.

Authors:  Marek Malik; Christine Garnett; Katerina Hnatkova; Jose Vicente; Lars Johannesen; Norman Stockbridge
Journal:  Drug Saf       Date:  2019-03       Impact factor: 5.606
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.