Literature DB >> 21699770

Characteristics of the enteroaggregative Shiga toxin/verotoxin-producing Escherichia coli O104:H4 strain causing the outbreak of haemolytic uraemic syndrome in Germany, May to June 2011.

F Scheutz1, E Møller Nielsen, J Frimodt-Møller, N Boisen, S Morabito, R Tozzoli, J P Nataro, A Caprioli.   

Abstract

The Escherichia coli strain causing a large outbreak of haemolytic uraemic syndrome and bloody diarrhoea in Germany in May and June 2011 possesses an unusual combination of pathogenic features typical of enteroaggregative E. coli together with the capacity to produce Shiga toxin. Through rapid national and international exchange of information and strains the known occurrence in humans was quickly assessed.We describe simple diagnostic screening tools to detect the outbreak strain in clinical specimens and a novel real-time PCR for its detection in foods.

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Year:  2011        PMID: 21699770     DOI: 10.2807/ese.16.24.19889-en

Source DB:  PubMed          Journal:  Euro Surveill        ISSN: 1025-496X


  81 in total

Review 1.  Shiga toxin-associated hemolytic uremic syndrome: advances in pathogenesis and therapeutics.

Authors:  Tania N Petruzziello-Pellegrini; Philip A Marsden
Journal:  Curr Opin Nephrol Hypertens       Date:  2012-07       Impact factor: 2.894

2.  Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.

Authors:  Yonatan H Grad; Marc Lipsitch; Michael Feldgarden; Harindra M Arachchi; Gustavo C Cerqueira; Michael Fitzgerald; Paul Godfrey; Brian J Haas; Cheryl I Murphy; Carsten Russ; Sean Sykes; Bruce J Walker; Jennifer R Wortman; Sarah Young; Qiandong Zeng; Amr Abouelleil; James Bochicchio; Sara Chauvin; Timothy Desmet; Sharvari Gujja; Caryn McCowan; Anna Montmayeur; Scott Steelman; Jakob Frimodt-Møller; Andreas M Petersen; Carsten Struve; Karen A Krogfelt; Edouard Bingen; François-Xavier Weill; Eric S Lander; Chad Nusbaum; Bruce W Birren; Deborah T Hung; William P Hanage
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-06       Impact factor: 11.205

3.  The fimbriae of enteroaggregative Escherichia coli induce epithelial inflammation in vitro and in a human intestinal xenograft model.

Authors:  Erik J Boll; Carsten Struve; Anja Sander; Zachary Demma; James P Nataro; Beth A McCormick; Karen A Krogfelt
Journal:  J Infect Dis       Date:  2012-06-21       Impact factor: 5.226

4.  Investigating the Relatedness of Enteroinvasive Escherichia coli to Other E. coli and Shigella Isolates by Using Comparative Genomics.

Authors:  Tracy H Hazen; Susan R Leonard; Keith A Lampel; David W Lacher; Anthony T Maurelli; David A Rasko
Journal:  Infect Immun       Date:  2016-07-21       Impact factor: 3.441

5.  Virulence of the Shiga toxin type 2-expressing Escherichia coli O104:H4 German outbreak isolate in two animal models.

Authors:  Tonia Zangari; Angela R Melton-Celsa; Aruna Panda; Nadia Boisen; Mark A Smith; Ivan Tatarov; Louis J De Tolla; James P Nataro; Alison D O'Brien
Journal:  Infect Immun       Date:  2013-02-25       Impact factor: 3.441

Review 6.  Epidemiology and clinical manifestations of enteroaggregative Escherichia coli.

Authors:  Betina Hebbelstrup Jensen; Katharina E P Olsen; Carsten Struve; Karen Angeliki Krogfelt; Andreas Munk Petersen
Journal:  Clin Microbiol Rev       Date:  2014-07       Impact factor: 26.132

7.  Novel aggregative adherence fimbria variant of enteroaggregative Escherichia coli.

Authors:  Rie Jønsson; Carsten Struve; Nadia Boisen; Ramona Valentina Mateiu; Araceli E Santiago; Håvard Jenssen; James P Nataro; Karen A Krogfelt
Journal:  Infect Immun       Date:  2015-01-26       Impact factor: 3.441

8.  Comparison of three different methods for detection of Shiga toxin-producing Escherichia coli in a tertiary pediatric care center.

Authors:  Emilie Vallières; Maude Saint-Jean; Fabien Rallu
Journal:  J Clin Microbiol       Date:  2012-11-21       Impact factor: 5.948

9.  Thrombotic microangiopathy: E. coli O104:H4 German outbreak: a missed opportunity.

Authors:  Piero Ruggenenti; Giuseppe Remuzzi
Journal:  Nat Rev Nephrol       Date:  2012-09-04       Impact factor: 28.314

10.  Prevalence of enteroaggregative Escherichia coli and its virulence-related genes in a case-control study among children from north-eastern Brazil.

Authors:  Ila Fernanda Nunes Lima; Nadia Boisen; Josiane da Quetz Silva; Alexandre Havt; Eunice Bobo de Carvalho; Alberto Melo Soares; Noélia Leal Lima; Rosa Maria Salani Mota; James P Nataro; Richard Littleton Guerrant; Aldo Ângelo Moreira Lima
Journal:  J Med Microbiol       Date:  2013-02-21       Impact factor: 2.472

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