| Literature DB >> 21699171 |
Suresh E Kurhade1, Abbas I Sanchawala, Velayutham Ravikumar, Debnath Bhuniya, D Srinivasa Reddy.
Abstract
The first total synthesis of isofregenedadiol, a bicyclic diterpene isolated from H. Viscosum, is reported starting from a D-(-)-pantolactone chiral pool. A one-pot quadruple reaction sequence comprising an enyne ring-closing metathesis/cross-metathesis/Diels-Alder/aromatization for the construction of a target skeleton is the highlight of the present synthesis.Entities:
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Year: 2011 PMID： 21699171 DOI： 10.1021/ol201336x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005