Literature DB >> 21697716

Pigment epithelium-derived factor: a not so sympathetic regulator of insulin resistance?

Christopher Bell1.   

Abstract

Pigment epithelium-derived factor (PEDF), an adipokine, is a regulator of oxidative stress, inflammation, angiogenesis, and insulin sensitivity. Contrary to animal and cell culture data, inhibition of the sympathoadrenal system does not affect serum PEDF in humans. However, during acute beta-adrenergic receptor stimulation serum PEDF concentration is decreased. PEDF may be involved in cross talk between adipose tissue and skeletal muscle.

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Year:  2011        PMID： 21697716     DOI： 10.1097/JES.0b013e31822673f0

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN： 0091-6331            Impact factor:   6.230


  6 in total

1.  Elevated plasma pigment epithelium-derived factor in children with type 2 diabetes mellitus is attributable to obesity.

Authors:  Jeanie B Tryggestad; Joshua J Wang; Sarah X Zhang; David M Thompson; Kevin R Short
Journal:  Pediatr Diabetes       Date:  2014-10-08       Impact factor: 4.866

2.  Sympathetic inhibition attenuates hypoxia induced insulin resistance in healthy adult humans.

Authors:  Garrett L Peltonen; Rebecca L Scalzo; Melani M Schweder; Dennis G Larson; Gary J Luckasen; David Irwin; Karyn L Hamilton; Thies Schroeder; Christopher Bell
Journal:  J Physiol       Date:  2012-04-10       Impact factor: 5.182

3.  Regulators of human white adipose browning: evidence for sympathetic control and sexual dimorphic responses to sprint interval training.

Authors:  Rebecca L Scalzo; Garrett L Peltonen; Gregory R Giordano; Scott E Binns; Anna L Klochak; Hunter L R Paris; Melani M Schweder; Steve E Szallar; Lacey M Wood; Dennis G Larson; Gary J Luckasen; Matthew S Hickey; Christopher Bell
Journal:  PLoS One       Date:  2014-03-06       Impact factor: 3.240

4.  A descriptive study of facial acanthosis nigricans and its association with body mass index, waist circumference and insulin resistance using HOMA2 IR.

Authors:  Shyam Verma; Resham Vasani; Rajiv Joshi; Meghana Phiske; Pritesh Punjabi; Tushar Toprani
Journal:  Indian Dermatol Online J       Date:  2016 Nov-Dec

5.  Facial Acanthosis Nigricans: A Morphological Marker of Metabolic Syndrome.

Authors:  Saumya Panda; Anupam Das; Koushik Lahiri; Manas Chatterjee; Tanmay Padhi; Sanjay Rathi; Sandipan Dhar; Nilendu Sarma
Journal:  Indian J Dermatol       Date:  2017 Nov-Dec       Impact factor: 1.494

6.  Metformin inhibits expression and secretion of PEDF in adipocyte and hepatocyte via promoting AMPK phosphorylation.

Authors:  Shumin Yang; Qiong Lv; Ting Luo; Lulu Liu; Rufei Gao; Shumei Chen; Peng Ye; Qingfeng Cheng; Qifu Li
Journal:  Mediators Inflamm       Date:  2013-10-31       Impact factor: 4.711
  6 in total

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