Literature DB >> 21696857

Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.

Eric D Lamarre1, Rahul Seth, Robert R Lorenz, Ramon Esclamado, David J Adelstein, Cristina P Rodriguez, Jerrold Saxton, Joseph Scharpf.   

Abstract

BACKGROUND: T1 and T2 tonsillar squamous cell cancer with limited neck disease can be managed with single-modality radiation or surgery. Over 11 years, 17 patients underwent radical tonsillectomies; and 33 patients underwent radiation-based treatments for T1 and T2 and N0 to N2a tonsil cancer. Patients were intended to receive single-modality treatment based on presentation; however, some ultimately received adjuvant treatments.
METHODS: A retrospective chart review to compare overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC) between the groups was used.
RESULTS: In surgical group, of 17 patients, 11 underwent surgery alone, 3 underwent surgery and radiation, and 3 underwent surgery with concurrent chemoradiation. Five-year OS for the surgical and radiation groups was 93% and 72%, respectively (no significance achieved). Five-year DSS rates (93% and 80%) and LRC (69% and 89%) similarly did not yield any significant difference.
CONCLUSION: Surgery remains a viable option in the management of T1 and T2 tonsillar cancers with comparable LRC, OS, and DSS.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21696857     DOI: 10.1016/j.amjoto.2011.02.005

Source DB:  PubMed          Journal:  Am J Otolaryngol        ISSN: 0196-0709            Impact factor:   1.808


  3 in total

1.  Outcome of transoral robotic surgery for stage I-II oropharyngeal cancer.

Authors:  J W L van Loon; L E Smeele; F J M Hilgers; M W M van den Brekel
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-08       Impact factor: 2.503

2.  Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil.

Authors:  Martin Canis; Alexios Martin; Martina Kron; Alexandra Konstantinou; Friedrich Ihler; Hendrik A Wolff; Christoph Matthias; Wolfgang Steiner
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-12-29       Impact factor: 2.503

3.  Avoidance of postoperative irradiation for cervical lymph node metastases of human papillomavirus-related tonsillar cancer.

Authors:  Koji Ebisumoto; Kenji Okami; Daisuke Maki; Kosuke Saito; Fukuko Shimizu; Takanobu Teramura; Shoji Kaneda; Masahiro Iida
Journal:  Laryngoscope Investig Otolaryngol       Date:  2017-03-10
  3 in total

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