Literature DB >> 2169559

Fetal and maternal levels of corticosterone and ACTH after pharmacological adrenalectomy.

T Z Baram1, L Schultz.   

Abstract

A paradigm of pharmacological adrenalectomy of pregnant rats and fetuses in utero is described. A regimen of twice daily metyrapone injections (10 mg/100 gm body weight), results in marked depression of serum corticosterone in pregnant and in fetal rats without surgical trauma and stress. The technique should be useful in a wide variety of studies involving the developing brain-adrenal axis.

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Year:  1990        PMID： 2169559     DOI： 10.1016/0024-3205(90)90607-s

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  10 in total

1.  Abnormal corticosterone regulation in an immature rat model of continuous chronic stress.

Authors:  E E Gilles; L Schultz; T Z Baram
Journal:  Pediatr Neurol       Date:  1996-09       Impact factor: 3.372

2.  Stress-induced transcriptional regulation in the developing rat brain involves increased cyclic adenosine 3',5'-monophosphate-regulatory element binding activity.

Authors:  C G Hatalski; T Z Baram
Journal:  Mol Endocrinol       Date:  1997-12

3.  Glucocorticoid effects on the programming of AT1b angiotensin receptor gene methylation and expression in the rat.

Authors:  Irina Bogdarina; Andrea Haase; Simon Langley-Evans; Adrian J L Clark
Journal:  PLoS One       Date:  2010-02-16       Impact factor: 3.240

Review 4.  The central corticotropin releasing factor system during development and adulthood.

Authors:  Aniko Korosi; Tallie Z Baram
Journal:  Eur J Pharmacol       Date:  2008-01-19       Impact factor: 4.432

5.  ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone.

Authors:  T Z Baram; L Schultz
Journal:  Epilepsia       Date:  1995-02       Impact factor: 5.864

6.  Feeding pregnant rats a low-protein diet alters the hepatic expression of SREBP-1c in their offspring via a glucocorticoid-related mechanism.

Authors:  Aml Erhuma; Sarah McMullen; Simon C Langley-Evans; Andrew J Bennett
Journal:  Endocrine       Date:  2009-08-12       Impact factor: 3.633

7.  Corticotropin-releasing hormone mediates the response to cold stress in the neonatal rat without compensatory enhancement of the peptide's gene expression.

Authors:  S J Yi; T Z Baram
Journal:  Endocrinology       Date:  1994-12       Impact factor: 4.736

8.  Brain-adrenal axis hormones are altered in the CSF of infants with massive infantile spasms.

Authors:  T Z Baram; W G Mitchell; O C Snead; E J Horton; M Saito
Journal:  Neurology       Date:  1992-06       Impact factor: 9.910

9.  Corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat.

Authors:  T Z Baram; L Schultz
Journal:  Brain Res Dev Brain Res       Date:  1991-07-16

10.  Effects of maternal and sibling deprivation on basal and stress induced hypothalamic-pituitary-adrenal components in the infant rat.

Authors:  S Avishai-Eliner; S J Yi; C J Newth; T Z Baram
Journal:  Neurosci Lett       Date:  1995-06-02       Impact factor: 3.046
  10 in total

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