| Literature DB >> 21693328 |
O Uskudar1, K Raja, T D Schiano, M I Fiel, J del Rio Martin, C Chang.
Abstract
Liver metastases from colorectal cancer are an absolute contraindication for liver transplantation. Aggressive therapy with liver resection and local chemotherapy in selected patients may be able to provide long-term cure. Given the risks of tumor recurrence, whether patients with post chemotherapy complications leading to liver failure should be offered transplantation is a challenging question in an era of limited organ availability. Herein we have presented 2 cases of liver transplantation performed in patients with colorectal cancer metastases treated with liver resection followed by hepatic artery infusion chemotherapy leading to development of sclerosing cholangitis and eventual liver failure. This report demonstrates that liver transplantation may be an option in selected patients with colorectal cancer liver metastases that have been well treated.Entities:
Mesh：
Year: 2011 PMID： 21693328 DOI： 10.1016/j.transproceed.2011.03.052
Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066