Literature DB >> 21692719

A therapeutic equivalence program: evidence-based promotion of more efficient use of medicines.

Ian Larmour1, Silvana Pignataro, Kerryn L Barned, Stav Mantas, Melvyn G Korman.   

Abstract

OBJECTIVE: The development of an effective therapeutic equivalence program (TEP) through the collaborative support of medical staff, using the principles of disinvestment. DESIGN AND
SETTING: A TEP was introduced at Southern Health, a metropolitan health service in Melbourne, in the 2006-07 financial year. Therapeutic classes were selected for the TEP by stakeholder consensus, and a preferred medication for each class was selected on the basis of cost considerations and therapeutic equivalence. New patients were commenced on preferred medicines, but patients receiving another medicine from a therapeutic class included in the program were not automatically switched to the preferred medicine. For the first 4 years of the program, prescribing patterns were monitored, and savings achieved (due to lower prices for and increased use of preferred medicines) were calculated on a monthly basis. MAIN OUTCOME MEASURES: Prescribing trends for preferred medicines, as a measure of acceptance of the TEP, and savings produced by the program.
RESULTS: Over the 4-year study period, 11 therapeutic classes were targeted. The use of all preferred medicines increased once they become part of the TEP and a total of $3.16 million was saved. The annual savings increased each year, and the rate of increase was six times that of the increase in patient separations.
CONCLUSIONS: The TEP at Southern Health resulted in significant savings. It showed that, by using a collaborative and evidence-based approach, the principles of disinvestment can be applied to use of medicines.

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Mesh:

Year:  2011        PMID: 21692719

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  4 in total

1.  Systematic literature review of the methodology for developing pharmacotherapeutic interchange guidelines and their implementation in hospitals and ambulatory care settings.

Authors:  Maria Adrover-Rigo; Maria-Dolores Fraga-Fuentes; Francesc Puigventos-Latorre; Iciar Martinez-Lopez
Journal:  Eur J Clin Pharmacol       Date:  2018-10-19       Impact factor: 2.953

2.  Sustainability in Health care by Allocating Resources Effectively (SHARE) 6: investigating methods to identify, prioritise, implement and evaluate disinvestment projects in a local healthcare setting.

Authors:  Claire Harris; Kelly Allen; Vanessa Brooke; Tim Dyer; Cara Waller; Richard King; Wayne Ramsey; Duncan Mortimer
Journal:  BMC Health Serv Res       Date:  2017-05-25       Impact factor: 2.655

3.  Sustainability in Health care by Allocating Resources Effectively (SHARE) 7: supporting staff in evidence-based decision-making, implementation and evaluation in a local healthcare setting.

Authors:  Claire Harris; Kelly Allen; Cara Waller; Tim Dyer; Vanessa Brooke; Marie Garrubba; Angela Melder; Catherine Voutier; Anthony Gust; Dina Farjou
Journal:  BMC Health Serv Res       Date:  2017-06-21       Impact factor: 2.655

4.  Sustainability in Health care by Allocating Resources Effectively (SHARE) 10: operationalising disinvestment in a conceptual framework for resource allocation.

Authors:  Claire Harris; Sally Green; Adam G Elshaug
Journal:  BMC Health Serv Res       Date:  2017-09-08       Impact factor: 2.655

  4 in total

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