BACKGROUND: Chronic kidney disease (CKD) is a predictor of increased mortality in patients undergoing coronary artery bypass surgery (CABG). OBJECTIVE: To evaluate the characteristics and predictors of increased mortality in the CKD population submitted to CABG. To compare in-hospital outcomes between patients with and without CKD, and with and without development of acute renal failure (ARF). METHODS: Retrospective analysis of a prospective database of all isolated CABG performed in a single public tertiary hospital from 1999 to 2007. CKD was considered when creatinine > 1.5 mg/dl. Clinical characteristics, mortality and post-operative complications were evaluated according to renal function. RESULTS: Of 3,890 patients, 362 (9.3%) had CKD. This population was older, presented grater prevalence of hypertension, left ventricular dysfunction, previous stroke, peripheral vascular disease and three-vessel disease. In-hospital outcomes revealed greater incidence of stroke (5.5% vs 2.1%), atrial fibrillation (16 vs 8.3%), low cardiac ouput syndrome (14.4% vs 8.5%), longer stay in intensive care unit (4.04 vs 2.83 days), and greater mortality (10.5% vs 3.8%). Logistic regression: female gender, smoking, diabetes and peripheral vascular disease were associated with higher in-hospital mortality within the CKD group. Patients who did not develop post-operative ARF presented 3.5% mortality; non-dialytic ARF: 35.4%; dialytic ARF: 66.7% mortality. Mortality was directly related to the stage of CKD, according to glomerular filtration rate. CONCLUSION: CKD patients submitted to CABG represent a high risk population, with increased incidence of complications and mortality. Post-operative ARF is a strong in-hospital mortality predictor. Glomerular filtration rate was inversely related to mortality.
BACKGROUND:Chronic kidney disease (CKD) is a predictor of increased mortality in patients undergoing coronary artery bypass surgery (CABG). OBJECTIVE: To evaluate the characteristics and predictors of increased mortality in the CKD population submitted to CABG. To compare in-hospital outcomes between patients with and without CKD, and with and without development of acute renal failure (ARF). METHODS: Retrospective analysis of a prospective database of all isolated CABG performed in a single public tertiary hospital from 1999 to 2007. CKD was considered when creatinine > 1.5 mg/dl. Clinical characteristics, mortality and post-operative complications were evaluated according to renal function. RESULTS: Of 3,890 patients, 362 (9.3%) had CKD. This population was older, presented grater prevalence of hypertension, left ventricular dysfunction, previous stroke, peripheral vascular disease and three-vessel disease. In-hospital outcomes revealed greater incidence of stroke (5.5% vs 2.1%), atrial fibrillation (16 vs 8.3%), low cardiac ouput syndrome (14.4% vs 8.5%), longer stay in intensive care unit (4.04 vs 2.83 days), and greater mortality (10.5% vs 3.8%). Logistic regression: female gender, smoking, diabetes and peripheral vascular disease were associated with higher in-hospital mortality within the CKD group. Patients who did not develop post-operative ARF presented 3.5% mortality; non-dialytic ARF: 35.4%; dialytic ARF: 66.7% mortality. Mortality was directly related to the stage of CKD, according to glomerular filtration rate. CONCLUSION: CKD patients submitted to CABG represent a high risk population, with increased incidence of complications and mortality. Post-operative ARF is a strong in-hospital mortality predictor. Glomerular filtration rate was inversely related to mortality.
Authors: Márcio Campos Sampaio; Carlos Alberto Gonçalves Máximo; Carolina Moreira Montenegro; Diandro Marinho Mota; Tatiana Rocha Fernandes; Antonio Carlos Mugayar Bianco; Celso Amodeo; Antonio Carlos Cordeiro Journal: Arq Bras Cardiol Date: 2013-06-11 Impact factor: 2.000
Authors: Matheus Miranda; João Nelson Rodrigues Branco; Guilherme Flora Vargas; Nelson Americo Hossne; Michele Costa Yoshimoto; José Honorio de Almeida Palma da Fonseca; José Osmar Medina de Abreu Pestana; Enio Buffolo Journal: Arq Bras Cardiol Date: 2016-12 Impact factor: 2.000
Authors: Matheus Miranda; Nelson Américo Hossne; João Nelson Rodrigues Branco; Guilherme Flora Vargas; José Honório de Almeida Palma da Fonseca; José Osmar Medina de Abreu Pestana; Yara Juliano; Enio Buffolo Journal: Arq Bras Cardiol Date: 2014-02 Impact factor: 2.000
Authors: Camila P S Arthur; Omar A V Mejia; Diogo Osternack; Marcelo Arruda Nakazone; Maxim Goncharov; Luiz A F Lisboa; Luís A O Dallan; Pablo M A Pomerantzeff; Fabio B Jatene Journal: Arq Bras Cardiol Date: 2017-09-04 Impact factor: 2.000