| Literature DB >> 21691626 |
Monica Breurken1, Edith H M Lempens, E W Meijer, Maarten Merkx.
Abstract
A protease-activatable collagen targeting probe (proCNA35) is synthesized by conjugation of a synthetic collagen fragment to the collagen binding protein CNA35 via a protease-cleavable linker. Cleavage of the linker by MMP1 releases the intramolecular inhibition of the collagen binding site and restores its collagen binding capacity.Entities:
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Year: 2011 PMID： 21691626 DOI： 10.1039/c1cc11964h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222