Literature DB >> 21690625

Opportunistic infection-associated immune reconstitution syndrome in transplant recipients.

Hsin-Yun Sun1, Nina Singh.   

Abstract

Reversal of pathogen-induced immunosuppression upon employment of effective antimicrobial therapy and withdrawal of iatrogenic immunosuppression has the potential to shift the host immune repertoire towards pathologic inflammatory responses conducive to immune reconstitution syndrome (IRS). Posttransplant IRS has been observed with fungi, M. tuberculosis, cytomegalovirus, and polyoma virus nephropathy. This review discusses the existing state of knowledge regarding IRS and the immune mechanisms that underlie its pathogenesis, with significant implications for developing reliable diagnostic biomarkers and optimal management strategies for post-transplant opportunistic infection-associated IRS.

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Year:  2011        PMID: 21690625     DOI: 10.1093/cid/cir276

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  32 in total

1.  [Immune reconstitution syndrome].

Authors:  D Meyer-Olson; D Ernst; M Stoll
Journal:  Z Rheumatol       Date:  2012-04       Impact factor: 1.372

Review 2.  The neurology of solid organ transplantation.

Authors:  J David Avila; Saša Živković
Journal:  Curr Neurol Neurosci Rep       Date:  2015-07       Impact factor: 5.081

Review 3.  The price of immunity.

Authors:  Romina S Goldszmid; Giorgio Trinchieri
Journal:  Nat Immunol       Date:  2012-09-18       Impact factor: 25.606

4.  Dectin immunoadhesins and pneumocystis pneumonia.

Authors:  David M Ricks; Kong Chen; Mingquan Zheng; Chad Steele; Jay K Kolls
Journal:  Infect Immun       Date:  2013-07-08       Impact factor: 3.441

Review 5.  Cryptococcosis.

Authors:  Eileen K Maziarz; John R Perfect
Journal:  Infect Dis Clin North Am       Date:  2016-03       Impact factor: 5.982

Review 6.  Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none.

Authors:  Daniel L Barber; Bruno B Andrade; Irini Sereti; Alan Sher
Journal:  Nat Rev Microbiol       Date:  2012-01-09       Impact factor: 60.633

7.  Disseminated Bacillus Calmette-Guérin (BCG) infection following allogeneic hematopoietic stem cell transplant in a patient with Bare Lymphocyte Syndrome type II.

Authors:  R F Abu-Arja; B E Gonzalez; M R Jacobs; L Cabral; R Egler; J Auletta; J Arnold; K R Cooke
Journal:  Transpl Infect Dis       Date:  2014-07-04       Impact factor: 2.228

8.  Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression.

Authors:  Hsin-Yun Sun; Barbara D Alexander; Shirish Huprikar; Graeme N Forrest; Didier Bruno; G Marshall Lyon; Dannah Wray; Leonard B Johnson; Costi D Sifri; Raymund R Razonable; Michele I Morris; Valentina Stosor; Marilyn M Wagener; Nina Singh
Journal:  Clin Infect Dis       Date:  2014-09-09       Impact factor: 9.079

9.  Neurological complications of solid organ transplantation.

Authors:  Amy A Pruitt; Francesc Graus; Myrna R Rosenfeld
Journal:  Neurohospitalist       Date:  2013-07

Review 10.  Invasive fungal infections in solid organ transplant recipients.

Authors:  Shmuel Shoham; Kieren A Marr
Journal:  Future Microbiol       Date:  2012-05       Impact factor: 3.165

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