Literature DB >> 21690506

Effect of endoscopic sinus surgery on pulmonary function and microbial pathogens in a pediatric population with cystic fibrosis.

Alexander J Osborn1, Randy Leung, Felix Ratjen, Adrian L James.   

Abstract

OBJECTIVE: To assess whether improvements in pulmonary function and microbial pathogenic findings can be achieved by endoscopic sinus surgery in a pediatric population with cystic fibrosis.
DESIGN: Retrospective medical record review.
SETTING: Academic research. PATIENTS: Forty-one patients with cystic fibrosis who had undergone endoscopic sinus surgery at a single tertiary academic pediatric otolaryngology practice. MAIN OUTCOME MEASURES: Changes in pulmonary function test values or respiratory tract microbial pathogens after endoscopic sinus surgery were examined.
RESULTS: Endoscopic sinus surgery did not improve pulmonary function test results in this population. Examination of respiratory tract microbial colonization showed that endoscopic sinus surgery did not affect microbial pathogens. The most common organisms isolated were Staphylococcus aureus and Pseudomonas aeruginosa.
CONCLUSION: The lack of effect of endoscopic sinus surgery on pulmonary function test results and respiratory tract microbial pathogens in our study highlights the need for prospective assessments of postoperative quality-of-life improvement and of adjunct medical therapy efficacy.

Entities:  

Mesh:

Year:  2011        PMID: 21690506     DOI: 10.1001/archoto.2011.68

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  9 in total

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Review 2.  Comprehensive review on endonasal endoscopic sinus surgery.

Authors:  Rainer K Weber; Werner Hosemann
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2015-12-22

3.  16S rRNA gene sequencing reveals site-specific signatures of the upper and lower airways of cystic fibrosis patients.

Authors:  Sarah K Lucas; Robert Yang; Jordan M Dunitz; Holly C Boyer; Ryan C Hunter
Journal:  J Cyst Fibros       Date:  2017-08-18       Impact factor: 5.482

4.  Nasal endoscopy and paranasal sinus computerised tomography (CT) findings in an Irish cystic fibrosis adult patient group.

Authors:  P Casserly; M Harrison; O O'Connell; N O'Donovan; B J Plant; P O'Sullivan
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-12-24       Impact factor: 2.503

Review 5.  Pathogenesis and management of nasal polyposis in cystic fibrosis.

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Review 6.  [Rhinosinusitis in cystic fibrosis].

Authors:  J G Mainz; A Gerber; C Arnold; J Baumann; I Baumann; A Koitschev
Journal:  HNO       Date:  2015-11       Impact factor: 1.284

Review 7.  Cystic Fibrosis.

Authors:  Kimberly M Dickinson; Joseph M Collaco
Journal:  Pediatr Rev       Date:  2021-02

8.  Cystic Fibrosis Foundation otolaryngology care multidisciplinary consensus recommendations.

Authors:  Adam J Kimple; Brent A Senior; Edward T Naureckas; David A Gudis; Ted Meyer; Sarah E Hempstead; Helaine E Resnick; Dana Albon; Wayne Barfield; Margo McKenna Benoit; Daniel M Beswick; Eliza Callard; Shelagh Cofer; Veronica Downer; E Claire Elson; Angela Garinis; Ashleigh Halderman; Lisa Hamburger; Meagan Helmick; Michael McCown; Cameron J McKinzie; Hanna Phan; Kenneth Rodriguez; Ronald C Rubenstein; Ashley Severin; Gopi Shah; Ambika Shenoy; Brittney Sprouse; Frank Virgin; Bradford A Woodworth; Stella E Lee
Journal:  Int Forum Allergy Rhinol       Date:  2022-02-22       Impact factor: 5.426

9.  Sinonasal manifestations in cystic fibrosis.

Authors:  Karin P Q Oomen; Max M April
Journal:  Int J Otolaryngol       Date:  2012-08-05
  9 in total

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