BACKGROUND: This study screened children in Beijing, China, in order to establish the validity of a Mandarin Chinese translation of the ASSQ. METHODS: We recruited children diagnosed with autism spectrum disorders (ASDs), attention deficit/hyperactivity disorder (ADHD), childhood-onset schizophrenia (COS) (DSM-IV diagnoses made independently by two senior psychiatrists) and unaffected children attending a public school in Beijing. Their parents were asked to complete the CH-ASSQ. RESULTS: Data from the parents of 94 children with ASD (mean age: 81 ± 47 months), 45 with ADHD (106 ± 27 months), 26 with COS (166 ± 36 months), and 120 unaffected control (72 ± 16 months) were collected. The total scores of ASSQ in children with ASD, ADHD, COS, and unaffected controls were 25.3 ± 9.2, 10.4 ± 7.1, 12.2 ± 10.6, and 5.2 ± 6.6 respectively. Total ASSQ scores of children with ASD were significantly higher than in any other group (all p < .0001). ROC analysis of ASD versus unaffected control subjects showed the area under curve was 0.957, with a cutoff of 12 having the maximum sensitivity (0.957) and specificity (0.825). CONCLUSIONS: Our pilot data suggest that CH-ASSQ successfully differentiates clinically diagnosed ASD patients from unaffected controls, as well as from patients with ADHD and COS. The instrument might therefore be useful for screening for ASD in urban Mandarin Chinese-speaking populations.
BACKGROUND: This study screened children in Beijing, China, in order to establish the validity of a Mandarin Chinese translation of the ASSQ. METHODS: We recruited children diagnosed with autism spectrum disorders (ASDs), attention deficit/hyperactivity disorder (ADHD), childhood-onset schizophrenia (COS) (DSM-IV diagnoses made independently by two senior psychiatrists) and unaffected children attending a public school in Beijing. Their parents were asked to complete the CH-ASSQ. RESULTS: Data from the parents of 94 children with ASD (mean age: 81 ± 47 months), 45 with ADHD (106 ± 27 months), 26 with COS (166 ± 36 months), and 120 unaffected control (72 ± 16 months) were collected. The total scores of ASSQ in children with ASD, ADHD, COS, and unaffected controls were 25.3 ± 9.2, 10.4 ± 7.1, 12.2 ± 10.6, and 5.2 ± 6.6 respectively. Total ASSQ scores of children with ASD were significantly higher than in any other group (all p < .0001). ROC analysis of ASD versus unaffected control subjects showed the area under curve was 0.957, with a cutoff of 12 having the maximum sensitivity (0.957) and specificity (0.825). CONCLUSIONS: Our pilot data suggest that CH-ASSQ successfully differentiates clinically diagnosed ASDpatients from unaffected controls, as well as from patients with ADHD and COS. The instrument might therefore be useful for screening for ASD in urban Mandarin Chinese-speaking populations.
Authors: Mari Hysing; Maj-Britt Posserud; Christopher Gillberg; Astri J Lundervold; Hilde K Ryland Journal: Child Adolesc Psychiatry Ment Health Date: 2012-11-12 Impact factor: 3.033
Authors: Franco De Crescenzo; Valentina Postorino; Martina Siracusano; Assia Riccioni; Marco Armando; Paolo Curatolo; Luigi Mazzone Journal: Front Psychiatry Date: 2019-02-21 Impact factor: 4.157
Authors: Mohammed Aldosari; Eric Fombonne; Hesham Aldhalaan; Mohammed Ouda; Saba Elhag; Hawraa Alshammari; Iman Ghazal; Asma Alsaleh; Tala Alqadoumi; Richard Thomson; Mohanad Al Khasawneh; Mohamed Tolefat; Fouad Alshaban Journal: Autism Date: 2019-01-03