Literature DB >> 21689936

Synthesis and anti-inflammatory activity of some novel 3-phenyl-N-[3-(4-phenylpiperazin-1yl)propyl]-1H-pyrazole-5-carboxamide derivatives.

Lingaiah Nagarapu1, Jhansi Mateti, Hanmant K Gaikwad, Rajashaker Bantu, M Sheeba Rani, N J Prameela Subhashini.   

Abstract

A new series of 3-phenyl-N-[3-(4-phenylpiperazin-1yl)propyl]-1H-pyrazole-5-carboxamide derivatives were synthesized and investigated their anti-inflammatory activities using carrageenan-induced rat paw edema model in vivo. All the synthesized compounds were found to be potent anti-inflammatory agents.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21689936     DOI： 10.1016/j.bmcl.2011.05.105

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Unusual rearrangement of imidazo[1,5-a]imidazoles and imidazo[1,2-b]pyrazoles into imidazo[1,5-a]pyrimidines and pyrazolo[1,5-a]pyrimidines.

Authors:  Khadija Gambouz; Mohsine Driowya; Mohammed Loubidi; Zahira Tber; Hassan Allouchi; Saïd El Kazzouli; Mohamed Akssira; Gérald Guillaumet
Journal:  RSC Adv       Date:  2019-09-16       Impact factor: 4.036

2.  Synthesis and cytotoxicity against tumor cells of pincer N-heterocyclic ligands and their transition metal complexes.

Authors:  Afaf Oulmidi; Smaail Radi; Abderrazak Idir; Abdelmajid Zyad; Imad Kabach; Mohamed Nhiri; Koen Robeyns; Aurelian Rotaru; Yann Garcia
Journal:  RSC Adv       Date:  2021-10-27       Impact factor: 4.036

Review 3.  Current status of pyrazole and its biological activities.

Authors:  Mohd Javed Naim; Ozair Alam; Farah Nawaz; Md Jahangir Alam; Perwaiz Alam
Journal:  J Pharm Bioallied Sci       Date:  2016 Jan-Mar
  3 in total

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