Acute Psychosis as the Initial Presentation of MS: A Case Report.

Psychiatric disorders have been commonly recognized to be associated with multiple sclerosis (MS) during the course of the illness or as a result of the side effects of the drugs used for its management. There have been reports of MS patirents, presenting initially with pure psychiatric symptoms. Amongst these, atypical psychosis has been infrequently reported to be a feature of MS; presentation with typical features of acute psychosis associated with stress appears to be very rare. Hence, this should always prompt for consideration of other diagnoses, including functional psychosis. Nonetheless, as illustrated by the following case report, acute onset of demyelinating diseases with the clinical phenotype of acute psychosis associated with stress may.